Optic Disc Melanocytoma Report of 5 Patients From Singapore With a Review of the Literature.

PURPOSE

The aim of this study was to report the clinical features of optic disc melanocytoma (ODMC).

DESIGN

This study was a retrospective case series.

METHODS

Five patients (6 eyes) with ODMC followed up over a mean duration of 3 years (range, 4-61 months) were included in this series.

RESULTS

The mean age of diagnosis was 55.2 years with Chinese female predominance. Four of 6 ODMCs were unilateral with predominance to the left side. Four patients had visual acuity of 6/9 or better at presentation, and all ODMCs were discovered incidentally. All ODMCs were black, with an average size of 0.8 disc diameter and partially covering the optic disc. Five of 6 ODMCs were inferiorly located and involved adjacent choroid and retina. Three of 6 ODMCs had ill-defined borders. Fundus fluorescein angiogram findings in 1 patient showed blocked fluorescence due to pigments. No loss of visual acuity of 2 or more Snellen lines, ODMC enlargement, or malignant transformation were noted in any patients during follow-up. There were no local complications. Ocular and systemic associations were not seen.

CONCLUSIONS

Our case series did not show any features of progression during our follow-up. Annual fundoscopic examinations are still important to detect enlargement and malignant transformation.