Benotsch Eric G, Zimmerman Rick S, Cathers Laurie, Pierce Juan, McNulty Shawn, Heck Ted, Perrin Paul B, Snipes Daniel J
Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, VA, USA Institute for Women's Health, Virginia Commonwealth University Richmond, VA , USA
St. Louis, College of Nursing, University of Missouri, St. Louis, MO, USA.
Int J STD AIDS. 2016 Aug;27(9):776-82. doi: 10.1177/0956462415595319. Epub 2015 Jul 15.
Male-to-female transgender women (TGW) experience high rates of substance use and HIV. A recent substance use trend is the use of prescription medication without a doctor's consent. No research to date has examined the associations between this non-medical use of prescription drugs and HIV risk behaviour in TGW. In the present study, TGW recruited from community venues (N = 104) in the Mid-Atlantic region of the United States completed surveys assessing demographic information, non-medical use of prescription drugs, other substance use, injection practices and sexual risk behaviour. Twenty-four per cent of the sample reported lifetime non-medical use of prescription drugs across the following categories: analgesics (21.2%), anxiolytics (14.4%), stimulants (12.5%) and sedatives (8.7%). Participants reporting non-medical use of prescription drugs were more likely to report other substance use, needle use to inject drugs, injecting silicone and sharing needles. In multivariable analyses, non-medical use of prescription drugs was associated with unprotected sex, sex after engaging in substance use, and commercial sex work, after controlling for demographic factors. Self-esteem and social support from family served as protective factors for non-medical use of prescription drugs. HIV-prevention programmes focused on TGW in the United States may wish to expand their assessment of substance use to include the use of prescription medications without a physician's consent.
男变女跨性别女性（TGW）存在较高的药物使用和感染艾滋病毒的比例。近期药物使用趋势是未经医生同意使用处方药。迄今为止，尚无研究探讨这种非医疗用途的处方药使用与TGW中艾滋病毒风险行为之间的关联。在本研究中，从美国大西洋中部地区社区场所招募的TGW（N = 104）完成了调查，评估人口统计学信息、非医疗用途的处方药使用、其他药物使用、注射行为和性风险行为。24%的样本报告在以下类别中有过终身非医疗用途的处方药使用：镇痛药（21.2%）、抗焦虑药（14.4%）、兴奋剂（12.5%）和镇静剂（8.7%）。报告非医疗用途的处方药使用的参与者更有可能报告其他药物使用、使用针头注射毒品、注射硅胶和共用针头。在多变量分析中，在控制人口统计学因素后，非医疗用途的处方药使用与无保护性行为、使用药物后性行为以及商业性工作有关。自尊和来自家庭的社会支持是预防非医疗用途的处方药使用的保护因素。美国针对TGW的艾滋病毒预防项目可能希望扩大对药物使用的评估，以包括未经医生同意使用处方药的情况。
