Ishiwata Sho, Yanagawa Takashi, Saito Kenichi, Takagishi Kenji
Orthopedics. 2015 Jul 1;38(7):e651-4. doi: 10.3928/01477447-20150701-93.
Developments in radiation therapy modalities offer alternative treatments for unresectable malignant tumors in the pelvis and trunk. However, poor vascularity as a result of radiation therapy makes the treated lesion susceptible to infection, and there are no established treatments for pelvic osteomyelitis with a large dead space after radiation therapy. The authors report 2 cases of sacral osteomyelitis after radiation therapy that were treated successfully with a gluteus maximus turnover flap. To create the flap, the distal portion of the lower third of the muscle was detached from the trochanter. The distal edge of the flap was turned toward the sacral defect and sewn to the remnant of the sacrum, which filled the dead space with the muscle bulk. A 68-year-old man with a recurrent sacral chordoma was treated with carbon ion radiation therapy; however, a sacral infection developed 5 months later. Debridement and a course of antibiotics could not control the infection and did not induce sufficient formation of granulation tissue in the large and deep dead space. The turnover flap with both gluteus maximus muscles cured the deep-seated infection and closed the wound. A 58-year-old woman had sacral osteoradionecrosis with infection. A turnover flap created with the left gluteus maximus muscle controlled the infection and closed the wound after the first operation, a V-Y flap, failed. This study showed that a gluteus maximus muscle turnover flap effectively controlled infectious lesions with large and deep dead space around the sacrum.
放射治疗方式的发展为盆腔和躯干不可切除的恶性肿瘤提供了替代治疗方法。然而,放射治疗导致的血管供应不良使治疗后的病变易受感染,且对于放疗后出现大死腔的盆腔骨髓炎尚无既定的治疗方法。作者报告了2例放疗后骶骨骨髓炎病例,通过臀大肌翻转皮瓣成功治愈。制作皮瓣时,将肌肉下三分之一的远端部分从转子处分离。将皮瓣的远端边缘转向骶骨缺损处并缝合至骶骨残余部分,肌肉块填充了死腔。一名68岁复发性骶骨脊索瘤男性患者接受了碳离子放射治疗;然而,5个月后出现了骶骨感染。清创和抗生素治疗未能控制感染,且在大而深的死腔内未诱导足够的肉芽组织形成。双侧臀大肌翻转皮瓣治愈了深部感染并闭合了伤口。一名58岁女性患有伴有感染的骶骨放射性骨坏死。在第一次手术(V-Y皮瓣)失败后,用左臀大肌制作的翻转皮瓣控制了感染并闭合了伤口。本研究表明,臀大肌翻转皮瓣能有效控制骶骨周围大而深的死腔感染性病变。