Bo'lshakova L O, Shenin Iu D, Fradkova T A, Ermolova O B, Astanina L N, Grigo'reva V M
Antibiot Khimioter. 1989 Oct;34(10):732-6.
Levorin and candicidin represent close mixtures of heptaenic components. Their physicochemical and biological properties were also close. The antibiotics showed similar diffusive properties in their assay by the agar diffusion method. This made it possible to determine activity of the Soviet levorin standard by the International candicidin standard. For defining the levorin unit in the international units of candicidin, a scaling ratio of 9 was proposed.
利佛菌素和杀假丝菌素是七烯类成分的近似混合物。它们的物理化学性质和生物学性质也相近。在用琼脂扩散法测定时,这两种抗生素表现出相似的扩散特性。这使得用国际杀假丝菌素标准来测定苏联利佛菌素标准品的活性成为可能。为了用杀假丝菌素的国际单位来定义利佛菌素单位,有人提出了9的换算比例。