Cimmino Alessio, Masi Marco, Evidente Marco, Evidente Antonio
Nat Prod Commun. 2015 Jun;10(6):1119-26.
This review deals with the isolation and chemical and biological characterization of phytotoxins produced by Ascochyta caulina and Phoma chenopodiicola proposed as mycoherbicides for the biological control of Chenopodium album, a worldwide spread weed which causes serious problems to some agrarian crops, including sugar beet and maize. Studies on the structure activity relationships and on the modes of actions of toxins isolated are also described, as well as the optimization of analytical methods focused on selection of the best fungal toxin producers. The attempts to scale up production of these phytotoxins aimed to obtain sufficient amounts for their application in greenhouse and field trials are also reported.
本综述涉及由茎点霉(Ascochyta caulina)和藜生茎点霉(Phoma chenopodiicola)产生的植物毒素的分离、化学和生物学特性,这些毒素被提议用作生物除草剂,用于对藜(Chenopodium album)进行生物防治。藜是一种在全球广泛分布的杂草,会给包括甜菜和玉米在内的一些农作物带来严重问题。文中还描述了对所分离毒素的构效关系和作用模式的研究,以及侧重于选择最佳真菌毒素产生菌的分析方法的优化。此外,还报道了扩大这些植物毒素产量的尝试,旨在获得足够数量用于温室和田间试验。