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[复苏后的窒息新生儿乳酸酸中毒]

[Lactic acidosis in recovered asphyctic newborn infants].

作者信息

Hernández-Ortega H, Angeles-Zepeda R, Maida-Claros R, Dehesa-Morales R, Molina-Sánchez A, Olvera-Guerrero A

出版信息

Bol Med Hosp Infant Mex. 1989 Oct;46(10):649-53.

PMID:2619915
Abstract

Thirty newborn babies delivered by elective caesarean section were studied. They were randomly placed in two groups. The first group consisted of newborns who scored 3 or less on the Apgar scale at one minute and 8 or more after five minutes. The other group included newborns which scored 8 or higher at one minute and 9 at five minutes. Blood samples were obtained from the umbilical cord which allowed for the measuring of the infants' pH, serum gases and pyruvic lactic acid levels. An increased level lactate was found in asphyctic infants. Five cases presented lactic acidosis which continued to be persistent in four of them an hour after they were born. Although increased levels of lactate were found also in the control group, they never presented lactic acidosis. No correlation was found between the pH and lactate levels nor between lactate and bicarbonate. A clear correlation between lactic acidosis and fetal distress was documented. It was concluded that lactate quantification is a useful indicator of neonatal asphyxia. Lactic acidosis; Apgar scores; asphyxia.

摘要

对30例择期剖宫产分娩的新生儿进行了研究。他们被随机分为两组。第一组由出生后1分钟阿氏评分3分及以下、5分钟后8分及以上的新生儿组成。另一组包括出生后1分钟评分8分及以上、5分钟评分9分的新生儿。从脐带采集血样,以测量婴儿的pH值、血清气体和丙酮酸乳酸水平。发现窒息婴儿的乳酸水平升高。5例出现乳酸酸中毒,其中4例出生后1小时仍持续存在。虽然对照组也发现乳酸水平升高,但他们从未出现乳酸酸中毒。pH值与乳酸水平之间、乳酸与碳酸氢盐之间均未发现相关性。记录到乳酸酸中毒与胎儿窘迫之间存在明显相关性。得出结论,乳酸定量是新生儿窒息的有用指标。乳酸酸中毒;阿氏评分;窒息。

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