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化学和微波消毒对义齿生物膜真菌的有效性及消毒对义齿基托适应性的影响

Effectiveness of Chemical and Microwave Disinfection on Denture Biofilm Fungi and the Influence of Disinfection on Denture Base Adaptation.

作者信息

Al-Saadi Mohannad H

机构信息

Department of Removable Prosthodontics, Faculty of Dentistry, Damascus University, P.O. Box 4926, Damascus, Syria.

出版信息

J Indian Prosthodont Soc. 2014 Dec;14(Suppl 1):24-30. doi: 10.1007/s13191-014-0354-2. Epub 2014 Feb 7.

DOI:10.1007/s13191-014-0354-2
PMID:26199488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4502004/
Abstract

The aims of this study were to evaluate the effectiveness of six disinfection methods and the influence of these methods on the adaptation of maxillary dentures. Acrylic resin specimens contaminated with fungi were exposed to the following disinfection treatments: 1. microwave oven (900 W) at full power for 5 min (with soaking the specimen in 250 ml water), 2. microwave oven at medium power for 5 min (with soaking the specimen in 250 ml water), 3. sodium hypochlorite 5.25 % for 5 min, 4. diluted sodium hypochlorite 1:420 for 5 h, 5. Chlorhexidine gluconate for 5 h, 6. effervescent tablets for 15 min, 7. soaking in 250 ml tap water for 15 min. Colony forming units (CFUs) of remaining cells were counted and compared with t test (p ≤ 0.05). Dimensional stability was evaluated using aluminum die simulating the maxillary edentulous arch. Posterior palatal gaps were measured. Data were analyzed using one-way ANOVA test and t test (p ≤ 0.05). Microwave irradiation (at full or medium power) and sodium hypochlorite 5.25 % for 5 min were able to reduce the CFUs of fungi by more than 4 log10 whereas diluted sodium hypochlorite, chlorhexidine gluconate, and effervescent tablets did not achieve a reduction of >2.8, 2.68 and 1.66, respectively. For dimensional stability test, t test revealed significant difference between control group and the microwave at full power group (p = 0.000). Within the limits of this study, microwave oven at medium power and sodium hypochlorite (5.25 %) are effective and safe methods of disinfecting removable dentures.

摘要

本研究的目的是评估六种消毒方法的有效性以及这些方法对上颌义齿适配性的影响。将被真菌污染的丙烯酸树脂标本进行以下消毒处理:1. 微波炉(900瓦)全功率5分钟(标本浸泡在250毫升水中);2. 微波炉中功率5分钟(标本浸泡在250毫升水中);3. 5.25%次氯酸钠5分钟;4. 稀释1:420的次氯酸钠5小时;5. 葡萄糖酸氯己定5小时;6. 泡腾片15分钟;7. 在250毫升自来水中浸泡15分钟。对剩余细胞的菌落形成单位(CFU)进行计数,并通过t检验进行比较(p≤0.05)。使用模拟上颌无牙弓的铝模评估尺寸稳定性。测量后腭间隙。数据采用单因素方差分析和t检验进行分析(p≤0.05)。微波照射(全功率或中功率)和5.25%次氯酸钠处理5分钟能够使真菌的CFU减少超过4个对数级,而稀释的次氯酸钠、葡萄糖酸氯己定和泡腾片分别未达到>2.8、2.68和1.66的减少量。对于尺寸稳定性测试,t检验显示对照组与全功率微波组之间存在显著差异(p = 0.000)。在本研究的范围内,中功率微波炉和次氯酸钠(5.25%)是消毒可摘义齿的有效且安全的方法。

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本文引用的文献

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Microwave irradiation as an alternative method for disinfection of denture base acrylic resins.微波辐照作为义齿基托丙烯酸树脂消毒的替代方法。
Minerva Stomatol. 2013 Jan-Feb;62(1-2):23-9.
2
Comparison of denture microwave disinfection and conventional antifungal therapy in the treatment of denture stomatitis: a randomized clinical study.义齿微波消毒与常规抗真菌治疗治疗义齿性口炎的效果比较:一项随机临床研究。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Oct;114(4):469-79. doi: 10.1016/j.oooo.2012.05.006.
3
Microwave denture disinfection versus nystatin in treating patients with well-controlled type 2 diabetes and denture stomatitis: a randomized clinical trial.微波义齿消毒与制霉菌素治疗 2 型糖尿病伴义齿性口炎患者的随机临床试验。
Int J Prosthodont. 2012 May-Jun;25(3):232-44.
4
Comparative evaluation of sodium hypochlorite and microwave disinfection on dimensional stability of denture bases.次氯酸钠和微波消毒对义齿基托尺寸稳定性的比较评价。
J Adv Prosthodont. 2012 Feb;4(1):24-9. doi: 10.4047/jap.2012.4.1.24. Epub 2012 Feb 29.
5
Adding denture cleanser to microwave disinfection regimen to reduce the irradiation time and the exposure of dentures to high temperatures.在微波消毒方案中添加假牙清洁剂,以减少照射时间和假牙暴露在高温下的时间。
Gerodontology. 2013 Mar;30(1):26-31. doi: 10.1111/j.1741-2358.2012.00641.x. Epub 2012 Mar 16.
6
Effectiveness of two disinfectant solutions and microwave irradiation in disinfecting complete dentures contaminated with methicillin-resistant Staphylococcus aureus.两种消毒剂和微波辐射对污染有耐甲氧西林金黄色葡萄球菌的全口义齿的消毒效果。
J Am Dent Assoc. 2012 Mar;143(3):270-7. doi: 10.14219/jada.archive.2012.0152.
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Evaluation of the occlusion vertical dimension of complete dentures after microwave disinfection.评价微波消毒后全口义齿的正中咬合垂直距离。
Gerodontology. 2012 Jun;29(2):e815-21. doi: 10.1111/j.1741-2358.2011.00567.x. Epub 2011 Oct 9.
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Microwave disinfection: cumulative effect of different power levels on physical properties of denture base resins.微波消毒:不同功率水平对义齿基托树脂物理性能的累积影响。
J Prosthodont. 2011 Dec;20(8):606-12. doi: 10.1111/j.1532-849X.2011.00770.x. Epub 2011 Oct 7.
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A conventional microwave oven for denture cleaning: a critical review.常规微波义齿清洗器:批判性评价。
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