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武里南医院小于胎龄儿和大于胎龄儿的危险因素

Risk Factors of Small for Gestational Age and Large for Gestational Age at Buriram Hospital.

作者信息

Luangkwan Supawadee, Vetchapanpasat Suppachoke, Panditpanitcha Pikul, Yimsabai Ratsadakorn, Subhaluksuksakom Pakwimon, Loyd Ryan Andrew, Uengarporn Naporn

出版信息

J Med Assoc Thai. 2015 May;98 Suppl 4:S71-8.

PMID:26201137
Abstract

BACKGROUND

Babies with low birth weight, small for gestational age (SGA) and large for gestational age (LGA) are at increased risk of many perinatal complications.

OBJECTIVE

To evaluate the risks factors associated with SGA and LGA births at Buriram Hospital.

MATERIAL AND METHOD

Pregnant women who were admitted to the labor room at Buriram hospital were selected, alternate cases in the daytime between October 2012 and January 2013. Pre-pregnancy BMI and gestational weight gain were categorized based on Institute of Medicine BMI groups. The predicted risk of either SGA or LGA births were estimated using generalized linear modeling and multivariate regression.

RESULTS

Data were collected on 197 pregnant women including pregnancy characteristics, antenatal care, labor characteristics, maternal complications and neonatal health. The average maternal age was 25.74 ± 6.47 years old. The results showed that the factors of weight gain during pregnancy < recommend for the pre-pregnancy BMI weight, gestational age < 37 weeks and pregnancy induce hypertension were correlated with SGA by logistic regression. Maternal age < 19 years old was correlated with a lower incidence of LGA. When using multivariate analysis the factor associated with SGA was gestational age < 37 weeks (Adjusted odds ratio 10.403, 95% CI 2.109-51.313, p = 0.004), whereas the factor associated with decreased LGA was maternal age < 19 years old (Adjusted odds ratio 0.128, 95% CI 0.017-0.983, p = 0.048).

CONCLUSION

The risk factor associated with SGA was gestational age < 37 weeks. The factor associated with LGA was maternal age, with maternal age < 19 years old having the least incidence for LGA. Public health programs should be targeted towards improving antenatal care screening and close monitoring including maternal age, gestational weight gain, monitoring obstetric care, prevent preterm delivery and providing proper newborn resuscitation in order to decrease perinatal complications and improve the quality of perinatal health.

摘要

背景

低出生体重、小于胎龄(SGA)和大于胎龄(LGA)的婴儿发生许多围产期并发症的风险增加。

目的

评估武里南医院SGA和LGA出生相关的风险因素。

材料与方法

选择入住武里南医院产房的孕妇,为2012年10月至2013年1月日间的交替病例。根据医学研究所的BMI分组对孕前BMI和孕期体重增加进行分类。使用广义线性模型和多变量回归估计SGA或LGA出生的预测风险。

结果

收集了197名孕妇的数据,包括妊娠特征、产前护理、分娩特征、母体并发症和新生儿健康状况。产妇平均年龄为25.74±6.47岁。结果显示,孕期体重增加低于孕前BMI推荐值、孕周<37周和妊娠高血压综合征等因素通过逻辑回归与SGA相关。产妇年龄<19岁与LGA发生率较低相关。多变量分析时,与SGA相关的因素是孕周<37周(调整优势比10.403,95%可信区间2.109 - 51.313,p = 0.004),而与LGA减少相关的因素是产妇年龄<19岁(调整优势比0.128,95%可信区间0.017 - 0.983,p = 0.048)。

结论

与SGA相关的风险因素是孕周<37周。与LGA相关的因素是产妇年龄,产妇年龄<19岁时LGA发生率最低。公共卫生项目应致力于改善产前护理筛查和密切监测,包括产妇年龄、孕期体重增加、监测产科护理、预防早产并提供适当的新生儿复苏,以减少围产期并发症并提高围产期健康质量。

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