Ray Anandasankar
Department of Entomology, Center for Disease Vector Research, University of California Riverside, Riverside, CA 92521, USA.
Curr Opin Neurobiol. 2015 Oct;34:158-64. doi: 10.1016/j.conb.2015.06.014. Epub 2015 Jul 17.
Mosquitoes use their sense of smell to find hosts, nectar, and oviposition sites, and to avoid repellents. A small number of mosquito species are adapted to feed on humans and have a major impact on public health by transmitting diseases such as malaria, dengue and filariasis. The application of odorants for behavioral control has not been fully realized yet due to complexity of the mosquito olfactory system. Recent progress in molecular and computational tools has enabled rigorous investigations of the mosquito olfactory system function and has started to reveal how specific receptors contribute to attractive and aversive behaviors. Here we discuss recent advances in linking odors to receptors and in exploiting this knowledge in finding attractants and repellents for mosquitoes.
蚊子利用嗅觉来寻找宿主、花蜜和产卵地点，并避开驱蚊剂。少数蚊子种类适应以人类为食，通过传播疟疾、登革热和丝虫病等疾病对公共卫生产生重大影响。由于蚊子嗅觉系统的复杂性，气味剂在行为控制方面的应用尚未完全实现。分子和计算工具的最新进展使得对蚊子嗅觉系统功能进行严格研究成为可能，并开始揭示特定受体如何促成吸引和厌恶行为。在此，我们讨论在将气味与受体联系起来以及利用这一知识寻找蚊子引诱剂和驱避剂方面的最新进展。
