Moscoso Felipe, Simian Daniela, Rivera Daniela, Acuña Guillermo, Quera Rodrigo
Rev Med Chil. 2015 Apr;143(4):531-5. doi: 10.4067/S0034-98872015000400017.
Fecal microbiota transplantation (FMT) has an incomparable efficacy to treat recurrent Clostridium difficile infection, with near 90% of success. We report a 57 years old woman who developed an antibiotic associated diarrhea with a positive polymerase chain reaction test for Clostridium Difficile toxin. She was successfully treated with Vancomycin trice but diarrhea recurred. Therefore a fecal microbiota transplant was performed using solid stools from a relative, diluted in saline and instilled in the distal ileon, with a good clinical response, without recurrence of diarrhea, during a 6-month follow-up.
粪便微生物群移植(FMT)在治疗复发性艰难梭菌感染方面具有无可比拟的疗效,成功率近90%。我们报告一名57岁女性,她出现了抗生素相关性腹泻,艰难梭菌毒素聚合酶链反应检测呈阳性。她先后三次使用万古霉素成功治疗,但腹泻复发。因此,使用来自一名亲属的固体粪便进行了粪便微生物群移植,粪便在盐水中稀释后注入回肠末端,临床反应良好,在6个月的随访期间腹泻未复发。