Haemers I, Delvallée M
Centre Hospitalier de Wallonie Picarde, Service de Gériatrie, CHwapi, Boulevard Lalaing 39, Tournai, Belgium.
Service d'Infectiologie, CHwapi, Tournai, Belgium.
Rev Med Brux. 2016;37(3):174-177.
Clostridium difficile infection is a major cause of nosocomial diarrhea. Its incidence has increased in the past 20 years and is associated with a significant morbidity and mortality. Relapsing is frequent after treatment and the management of these recurrent Clostridium difficile infections is challenging. Several studies over the years have shown that fecal microbiota transplantion is associated with a high degree of success. Fecal microbiota transplantion is now part of the European recommendations in the treatment of recurrent Clostridium difficile infections. However, standard procedures are needed to define indications, donor's selection criteria, preparation of the stool sample and its administration as well as the patients follow up. Illustration by a case report.
艰难梭菌感染是医院获得性腹泻的主要原因。在过去20年中其发病率有所上升，且与显著的发病率和死亡率相关。治疗后复发很常见，而这些复发性艰难梭菌感染的管理具有挑战性。多年来的多项研究表明，粪便微生物群移植具有很高的成功率。粪便微生物群移植现已成为欧洲复发性艰难梭菌感染治疗推荐的一部分。然而，需要标准程序来确定适应症、供体选择标准、粪便样本的制备及其给药以及患者随访。通过一例病例报告进行说明。
