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严重紊乱的生命体征作为低收入国家重症监护病房急性治疗调整的触发因素。

Severely deranged vital signs as triggers for acute treatment modifications on an intensive care unit in a low-income country.

作者信息

Schell Carl Otto, Castegren Markus, Lugazia Edwin, Blixt Jonas, Mulungu Moses, Konrad David, Baker Tim

机构信息

Centre for Clinical Research Sörmland, Uppsala University, Uppsala, Sweden.

Department of Internal Medicine, Medicinkliniken, Nyköping Hospital, Sörmland County Council, 61185, Nyköping, Sweden.

出版信息

BMC Res Notes. 2015 Jul 25;8:313. doi: 10.1186/s13104-015-1275-9.

Abstract

BACKGROUND

Critical care saves lives of the young with reversible disease. Little is known about critical care services in low-income countries. In a setting with a shortage of doctors the actions of the nurse bedside are likely to have a major impact on the outcome of critically ill patients with rapidly changing physiology. Identification of severely deranged vital signs and subsequent treatment modifications are the basis of modern routines in critical care, for example goal directed therapy and rapid response teams. This study assesses how often severely deranged vital signs trigger an acute treatment modification on an Intensive Care Unit (ICU) in Tanzania.

METHODS

A medical records based, observational study. Vital signs (conscious level, respiratory rate, oxygen saturation, heart rate and systolic blood pressure) were collected as repeated point prevalences three times per day in a 1-month period for all adult patients on the ICU. Severely deranged vital signs were identified and treatment modifications within 1 h were noted.

RESULTS

Of 615 vital signs studied, 126 (18%) were severely deranged. An acute treatment modification was in total indicated in 53 situations and was carried out three times (6%) (2/32 for hypotension, 0/8 for tachypnoea, 1/6 for tachycardia, 0/4 for unconsciousness and 0/3 for hypoxia).

CONCLUSIONS

This study suggests that severely deranged vital signs are common and infrequently lead to acute treatment modifications on an ICU in a low-income country. There may be potential to improve outcome if nurses are guided to administer acute treatment modifications by using a vital sign directed approach. A prospective study of a vital sign directed therapy protocol is underway.

摘要

背景

重症监护可挽救患有可逆性疾病的年轻人的生命。对于低收入国家的重症监护服务知之甚少。在医生短缺的情况下,护士在床边的操作可能会对生理状况迅速变化的重症患者的预后产生重大影响。识别严重紊乱的生命体征并随后调整治疗是重症监护现代常规操作的基础,例如目标导向治疗和快速反应小组。本研究评估在坦桑尼亚的一个重症监护病房(ICU)中,严重紊乱的生命体征引发急性治疗调整的频率有多高。

方法

一项基于病历的观察性研究。在1个月的时间里,每天3次以重复的点患病率形式收集ICU中所有成年患者的生命体征(意识水平、呼吸频率、血氧饱和度、心率和收缩压)。识别出严重紊乱的生命体征,并记录1小时内的治疗调整情况。

结果

在研究的615项生命体征中,126项(18%)严重紊乱。总共在53种情况下表明需要进行急性治疗调整,其中3次(6%)得到了执行(低血压情况中2/32得到执行;呼吸急促情况中0/8;心动过速情况中1/6;意识丧失情况中0/4;低氧情况中0/3)。

结论

本研究表明,严重紊乱的生命体征很常见,但在低收入国家的ICU中很少导致急性治疗调整。如果指导护士采用基于生命体征的方法进行急性治疗调整,可能有改善预后的潜力。一项关于基于生命体征的治疗方案的前瞻性研究正在进行中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f32/5501369/cd7e7d319e5f/13104_2015_1275_Fig1_HTML.jpg

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