Gu Yulong, Warren Jim, Kennelly John, Walker Natalie, Harwood Matire
University of Auckland, New Zealand.
Stud Health Technol Inform. 2015;214:81-6.
Diabetes is a common disease affecting 9% of the adult population worldwide. People with impaired glucose tolerance ('prediabetes') are at high risk of progressing to type 2 diabetes.
To understand prediabetes incidence rate, we analysed the electronic medical records (EMR) from 14 New Zealand general practices regarding patients aged ≥20 years and enrolled with the practices between 2009 and 2012. Prediabetes incidence rate was calculated by the number of patients with an initial HbA1c of 41-49 mmol/mol in 2011 among those who had not been diagnosed or treated for diabetes.
28,192 adults were included in the analysis, 11% of this cohort had diabetes before 2011. 1,276 new cases of prediabetes were identified in 2011, giving a 5.0% incidence rate. The relative risk (RR) for prediabetes was increased for the Māori and Pacific groups versus non-Māori/non-Pacific people, with RR of 1.97 in the younger age groups (<50 years) and RR of 1.42 in the 50+ group. The RR for having uncontrolled HbA1c (highest HbA1c in 2011 ≥65 mmol/mol) among the whole adult population was also increased for the Māori and Pacific groups versus non-Māori/non-Pacific people (RR=3.35 among those <50 years, RR=4.35 in the 50+ group).
EMR analysis identified an alarming incidence rate of prediabetes, especially among Māori and Pacific groups, highlighting the need to better prevent and manage the condition.
糖尿病是一种常见疾病,全球9%的成年人受其影响。糖耐量受损(“糖尿病前期”)患者进展为2型糖尿病的风险很高。
为了解糖尿病前期发病率,我们分析了来自新西兰14家全科诊所的电子病历(EMR),这些病历涉及2009年至2012年期间登记在册的年龄≥20岁的患者。糖尿病前期发病率通过2011年初始糖化血红蛋白(HbA1c)为41 - 49 mmol/mol且未被诊断或治疗过糖尿病的患者数量来计算。
28192名成年人纳入分析,该队列中11%的人在2011年之前患有糖尿病。2011年确诊1276例糖尿病前期新病例,发病率为5.0%。与非毛利/非太平洋人群相比,毛利人和太平洋人群患糖尿病前期的相对风险(RR)增加,在较年轻年龄组(<50岁)中RR为1.97,在50岁及以上组中RR为1.42。与非毛利/非太平洋人群相比,毛利人和太平洋人群中成年人群体糖化血红蛋白控制不佳(2011年最高HbA1c≥65 mmol/mol)的RR也增加(<50岁人群中RR = 3.35,50岁及以上组中RR = 4.35)。
电子病历分析发现糖尿病前期发病率惊人,尤其是在毛利人和太平洋人群中,这突出表明需要更好地预防和管理这种疾病。