Chen Xi, Li Jinrang
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Mar;29(6):499-504.
To investigate the effect of nasal surgery alone for OSAHS using Meta-analysis.
The published articles were searched from PubMed, Chinese Biomedical Literature CD-ROM databases, China Academic Journals Full-text database. The quality of the searched original studies were assessed and the outcomes with the requirements were analyzed.
Nineteen articles and 621 cases were finally included, including 15 English literatures and 4 Chinese literatures. The results of Meta analysis showed that: (1)The weighted mean between pre-and postoperative AHI was no significantly difference [weighted mean difference (WMD) = 0. 11, 95% CI (-0. 02,0. 23), P>0. 05]. (2) The nasal surgery alone significantly reduced theEpworth sleepiness scale scores in thirteen studies [WMD=0. 94,95% CI (0. 62,1. 26), P<. 01].
The meta-analyses show that nasal surgery alone can effectively improve the subjective clinical symptoms of patients with OSAHS. However, nasal surgery alone has a limited efficacy in treating OSAHS.
采用Meta分析探讨单纯鼻部手术治疗阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的效果。
从PubMed、中国生物医学文献光盘数据库、中国学术期刊全文数据库检索已发表的文章。对检索到的原始研究的质量进行评估，并对符合要求的结果进行分析。
最终纳入19篇文章和621例病例，其中英文文献15篇，中文文献4篇。Meta分析结果显示：（1）术前和术后呼吸暂停低通气指数（AHI）的加权均值无显著差异[加权均值差（WMD）=0.11，95%可信区间（CI）（-0.02，0.23），P>0.05]。（2）在13项研究中，单纯鼻部手术显著降低了爱泼沃斯思睡量表评分[WMD=0.94，95%CI（0.62，1.26），P<0.01]。
Meta分析表明，单纯鼻部手术可有效改善OSAHS患者的主观临床症状。然而，单纯鼻部手术治疗OSAHS的疗效有限。
