McAvoy Drew C, Pittinger Charles A, Willis Alison M
University of Cincinnati, Department of Biomedical, Chemical, and Environmental Engineering, 40 Engineering Research Center, Cincinnati, OH 45221, USA.
LLC, 6547 Edwood Avenue, Cincinnati, OH 45224, USA.
Ecotoxicol Environ Saf. 2016 Sep;131:143-50. doi: 10.1016/j.ecoenv.2015.07.009. Epub 2015 Jul 23.
The biotransformation of tetrabromobisphenol A (TBBPA) was evaluated in anaerobic digester sludge, soils, and freshwater sediments. In anaerobic digester sludge, TBBPA biotransformed rapidly with a 50% disappearance time (DT50) of 19 days, though little mineralization (1.1%) was observed. In aerobic soils, mineralization of TBBPA ranged from 17.5% to 21.6% with 55.3-83.6% of the TBBPA incorporated into the soils as a non-extractable bound residue. The DT50 for TBBPA in aerobic soils ranged from 5.3 to 7.7 days. In anaerobic soils, 48.3-100% of the TBBPA was incorporated into the soils as non-extractable bound residue with <4% mineralized. The soil fate studies demonstrated extensive incorporation of TBBPA into the solid matrix and this association was related to the amount of organic carbon in the soils (i.e., greater association of TBBPA with soil at higher organic carbon content). In anaerobic sediments the DT50 for TBBPA ranged from 28 to 42 days, whereas in aerobic sediments the DT50 for TBBPA ranged from 48 to 84 days and depended on the initial dose concentration. Most of the TBBPA in the sediment studies was incorporated as a non-extractable bound residue with little mineralization observed. Sediment extracts revealed three unknown biotransformation products and bisphenol A (BPA). These results were consistent with previously published studies where TBBPA biotransformed in anaerobic environments (digester sludge and sediments) by debromination and slowly mineralized in the test environments (anaerobic digester sludge, soils, and freshwater sediments).
在厌氧消化池污泥、土壤和淡水沉积物中评估了四溴双酚A（TBBPA）的生物转化情况。在厌氧消化池污泥中，TBBPA迅速发生生物转化，50%消失时间（DT50）为19天，不过观察到的矿化程度较低（1.1%）。在好氧土壤中，TBBPA的矿化率在17.5%至21.6%之间，55.3 - 83.6%的TBBPA以不可提取的结合残留物形式结合到土壤中。TBBPA在好氧土壤中的DT50为5.3至7.7天。在厌氧土壤中，48.3 - 100%的TBBPA以不可提取的结合残留物形式结合到土壤中，矿化率小于4%。土壤归宿研究表明TBBPA大量结合到固体基质中，这种结合与土壤中的有机碳含量有关（即TBBPA与有机碳含量较高的土壤结合更紧密）。在厌氧沉积物中，TBBPA的DT50为28至42天，而在好氧沉积物中，TBBPA的DT50为48至84天，且取决于初始剂量浓度。沉积物研究中的大多数TBBPA以不可提取的结合残留物形式结合，观察到的矿化程度较低。沉积物提取物显示出三种未知的生物转化产物和双酚A（BPA）。这些结果与先前发表的研究一致，即在厌氧环境（消化池污泥和沉积物）中，TBBPA通过脱溴作用发生生物转化，并在测试环境（厌氧消化池污泥、土壤和淡水沉积物）中缓慢矿化。
