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阻塞性结直肠癌治疗方法的研究

Investigation of treatment methods in obstructive colorectal cancer.

作者信息

Lin Bing-Qiang, Wang Rong-Lin, Li Qing-Xiang, Chen Wen, Huang Zheng-Yuan

机构信息

Department of Emergency Surgery, Union Hospital of Fujian Medical University, Fuzhou, China.

出版信息

J BUON. 2015 May-Jun;20(3):756-61.

PMID:26214627
Abstract

PURPOSE

The aim of this study was to explore the treatment strategies for patients with obstructive colorectal cancer at different sites.

METHODS

Treatment strategies were adopted according to the location of colorectal cancer and the condition of the patients when they were admitted to the hospital. Among a total of 134 patients, 29 patients were subjected to stent placement to relieve the obstruction before undergoing colorectal resection, 15 patients underwent per anum ileus catheterization to alleviate the symptoms of obstruction and waited for removal of the tumor within a limited time; 39 underwent intraoperative colonic lavage and colon resection with anastomosis and the remaining 51 patients were subjected to emergency surgery due to strangulation of the bowel, perforation, septic shock or other conditions before surgery.

RESULTS

Stent placement was successfully performed on 23 patients, with a success rate of 79%. Ninety-five of 134 patients (71% had stage I anastomosis and only one case had anastomotic fistula. Infection of incision happened in 9 (7%) cases and 2 (1.5%) patients died of infection.

CONCLUSIONS

Individualized treatment for patients with obstructive colorectal cancer can lead to tumor resection and stage I anastomosis, thereby avoiding the suffering of second-stage surgery or colostomy.

摘要

目的

本研究旨在探讨不同部位梗阻性结直肠癌患者的治疗策略。

方法

根据结直肠癌的位置及患者入院时的病情采取治疗策略。在总共134例患者中,29例患者在进行结直肠切除术前接受了支架置入以缓解梗阻,15例患者进行了经肛门肠梗阻导管置入以缓解梗阻症状并在有限时间内等待肿瘤切除;39例患者接受了术中结肠灌洗及结肠切除吻合术,其余51例患者因肠绞窄、穿孔、感染性休克或其他手术前情况而接受了急诊手术。

结果

23例患者成功进行了支架置入,成功率为79%。134例患者中有95例(71%)进行了一期吻合,仅有1例发生吻合口瘘。9例(7%)发生切口感染,2例(1.5%)患者死于感染。

结论

梗阻性结直肠癌患者的个体化治疗可实现肿瘤切除及一期吻合,从而避免二期手术或结肠造口的痛苦。

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1
Investigation of treatment methods in obstructive colorectal cancer.阻塞性结直肠癌治疗方法的研究
J BUON. 2015 May-Jun;20(3):756-61.
2
One-stage segmental colectomy and primary anastomosis after intraoperative colonic irrigation and total colonoscopy for patients with obstruction due to left-sided colorectal cancer.一期节段性结肠切除术和一期吻合术在术中结肠灌洗和全结肠镜检查后的左侧结直肠癌梗阻患者中的应用。
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Am J Gastroenterol. 2010 May;105(5):1087-93. doi: 10.1038/ajg.2009.660. Epub 2009 Nov 24.
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[The single-stage surgery of colorectal neoplastic occlusion. The experience of 133 cases].[结直肠肿瘤性梗阻的一期手术。133例经验]
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Staged surgery after colonic decompression may be safer for the treatment of obstructive left-sided colorectal cancer in a non-specialized hospital.在非专科医院,结肠减压后分期手术治疗左侧梗阻性结直肠癌可能更安全。
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引用本文的文献

1
Definition of large bowel obstruction by primary colorectal cancer: A systematic review.原发性结直肠癌所致大肠梗阻的定义:系统评价。
Colorectal Dis. 2021 Apr;23(4):787-804. doi: 10.1111/codi.15479. Epub 2021 Jan 15.
2
Lymphocyte-to-monocyte ratio effectively predicts survival outcome of patients with obstructive colorectal cancer.淋巴细胞与单核细胞比值可有效预测梗阻性结直肠癌患者的生存结局。
World J Gastroenterol. 2019 Sep 7;25(33):4970-4984. doi: 10.3748/wjg.v25.i33.4970.
3
Do Self-Expanding Metal Stents as a Bridge to Surgery Benefit All Patients with Obstructive Left-Side Colorectal Cancers?
自膨式金属支架作为手术桥梁对所有左侧梗阻性结直肠癌患者都有益吗?
Gastroenterol Res Pract. 2019 Feb 3;2019:7418348. doi: 10.1155/2019/7418348. eCollection 2019.