妊娠期急性阑尾炎的磁共振成像：一项为期5年的多机构研究。
Magnetic resonance imaging of acute appendicitis in pregnancy: a 5-year multiinstitutional study.
作者信息
Burke Lauren M B, Bashir Mustafa R, Miller Frank H, Siegelman Evan S, Brown Michele, Alobaidy Mamdoh, Jaffe Tracy A, Hussain Shahid M, Palmer Suzanne L, Garon Bonnie L, Oto Aytekin, Reinhold Caroline, Ascher Susan M, Demulder Danielle K, Thomas Stephen, Best Shaun, Borer James, Zhao Ken, Pinel-Giroux Fanny, De Oliveira Isabela, Resende Daniel, Semelka Richard C
机构信息
Department of Radiology, University of North Carolina, Chapel Hill, School of Medicine, Chapel Hill, NC.
Department of Radiology, Duke University Medical Center, Durham, NC.
出版信息
Am J Obstet Gynecol. 2015 Nov;213(5):693.e1-6. doi: 10.1016/j.ajog.2015.07.026. Epub 2015 Jul 26.
OBJECTIVE
The purpose of this study was to determine the diagnostic performance of magnetic resonance imaging (MRI) in the diagnosis of acute appendicitis during pregnancy in a multiinstitutional study.
STUDY DESIGN
In this multicenter retrospective study, the cases of pregnant women who underwent MRI evaluation of abdominal or pelvic pain and who had clinical suspicion of acute appendicitis between June 1, 2009, and July 31, 2014, were reviewed. All MRI examinations with positive findings for acute appendicitis were confirmed with surgical pathologic information. Sensitivity, specificity, negative predictive values, and positive predictive values were calculated. Receiver operating characteristic curves were generated, and area under the curve analysis was performed for each participating institution.
RESULTS
Of the cases that were evaluated, 9.3% (66/709) had MRI findings of acute appendicitis. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive values were 96.8%, 99.2%, 99.0%, 92.4%, and 99.7%, respectively. There was no statistically significant difference between centers that were included in the study (pair-wise probability values ranged from 0.12-0.99).
CONCLUSION
MRI is useful and reproducible in the diagnosis of suspected acute appendicitis during pregnancy.
目的
本研究旨在通过一项多机构研究确定磁共振成像（MRI）在诊断妊娠期急性阑尾炎中的诊断性能。
研究设计
在这项多中心回顾性研究中，对2009年6月1日至2014年7月31日期间因腹部或盆腔疼痛接受MRI评估且临床怀疑为急性阑尾炎的孕妇病例进行了回顾。所有急性阑尾炎MRI检查阳性结果均经手术病理信息证实。计算敏感性、特异性、阴性预测值和阳性预测值。生成受试者工作特征曲线，并对每个参与机构进行曲线下面积分析。
结果
在接受评估的病例中，9.3%（66/709）有急性阑尾炎的MRI表现。敏感性、特异性、准确性、阳性预测值和阴性预测值分别为96.8%、99.2%、99.0%、92.4%和99.7%。纳入研究的各中心之间无统计学显著差异（两两概率值范围为0.12 - 0.99）。
结论
MRI在诊断妊娠期疑似急性阑尾炎方面是有用且可重复的。
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