Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama 226-8503, Japan; CREST, Japan Science and Technology Agency, Saitama 332-0012, Japan.
Dev Cell. 2015 Jul 27;34(2):132-4. doi: 10.1016/j.devcel.2015.07.002.
Autophagy is involved in diverse cellular functions through degradation of various intracellular constituents, and hence must be tightly controlled. A recent study by Hu et al. (2015) in Nature Cell Biology adds a new layer of autophagy regulation, involving Tor kinase-driven degradation of mRNAs encoding autophagy-related proteins.
自噬通过降解各种细胞内成分参与多种细胞功能,因此必须受到严格控制。胡等人(2015)在《自然细胞生物学》上的一项最新研究增加了一个新的自噬调控层,涉及 Tor 激酶驱动的自噬相关蛋白编码 mRNA 的降解。