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球囊后凸成形术与短节段固定联合椎体成形术治疗Kümmell病的比较

Comparison between Balloon Kyphoplasty and Short Segmental Fixation Combined with Vertebroplasty in the Treatment of Kümmell's Disease.

作者信息

Chen Liang, Dong Renbin, Gu Yong, Feng Yu

机构信息

The First Affiliated Hospital of Soochow University, Department of Orthopaedic Surgery, China; Taizhou Hospital of Zhejiang Province, Department of Orthopaedic Surgery, China.

出版信息

Pain Physician. 2015 Jul-Aug;18(4):373-81.

PMID:26218941
Abstract

BACKGROUND

Kümmell's disease is a clinical syndrome characterized by a minor spinal trauma with a symptom-free period from months to years, followed by progressive painful kyphosis. Kyphoplasty and vertebroplasty have been introduced to treat Kümmell's disease, and obtained good clinical results. Recently, delayed cement displacement was reported for Kümmell's disease treated by cement augmentation alone. Some authors recommended internal fixation combined with cement injection for this particular condition.

OBJECTIVE

To evaluate and compare the clinical efficacy, especially the pain reduction, of 2 procedures (kyphoplasty alone versus short segmental fixation combined with vertebroplasty) in the treatment of Kümmell's disease.

STUDY DESIGN

Retrospective evaluation and comparison of postoperative VAS scores and radiographic outcomes.

SETTING

Single center inpatient population.

METHODS

Two procedures, including conventional balloon kyphoplasty and short segmental fixation combined with vertebroplasty, were utilized for 54 patients with Kümmell's disease. All patients were followed-up for 8-42 months. Visual analog scale (VAS), vertebral height, and local kyphotic angle were evaluated and compared for 2 groups before surgery, after surgery, and at final follow-up. Pearson correlation coefficients were calculated to assess the relationship between the decreased values of pain scores (VAS) and improvement of anterior vertebral height and local kyphotic angle.

RESULTS

For the KP group, the VAS pain score decreased significantly from 7.8 ± 0.9 before surgery to 3.3 ± 1.0 after surgery (P < 0.01), and 2.9 ± 0.9 at final follow-up (P < 0.01). The mean height of the anterior vertebral body increased from 14.8 ± 2.4 mm before surgery to 19.3 ± 2.1 mm after surgery (P < 0.01). The mean local kyphotic angle decreased from 22.7 ± 6.9° before surgery to 14.5 ± 5.3° after surgery (P < 0.01). For SSF + VP group, the VAS pain score decreased significantly from 7.2 ± 1.6 before surgery to 4.7 ± 1.3 after surgery (P < 0.01), and 3.5 ± 1.2 at final follow-up (P < 0.01). The mean height of the anterior vertebral body increased from 13.6 ± 2.5mm before surgery to 17.3 ± 2.7 mm after surgery (P < 0.01). The mean local kyphotic angle decreased from 24.7 ± 9.2° before surgery to 15.5 ± 6.2° after surgery (P < 0.01). No significant loss of correction of vertebral height and kyphosis was observed at follow-up. Improvement of VAS score had no correlation with improvement of vertebral height or local kyphotic angle. Asymptomatic cement leakage occurred in both groups.

LIMITATIONS

Retrospective study with a relatively small sample size.

CONCLUSIONS

This study showed that both balloon kyphoplasty alone and short segmental fixation combined with vertebroplasty for Kümmell's disease were safe and effective. Improvement of VAS score had no correlation with improvement of vertebral height or local kyphotic angle. Comparatively, balloon kyphoplasty resulted in same the clinical outcomes with less complications.

摘要

背景

Kümmell病是一种临床综合征,其特征为轻度脊柱创伤后有长达数月至数年的无症状期,随后出现进行性疼痛性脊柱后凸。椎体后凸成形术和椎体成形术已被用于治疗Kümmell病,并取得了良好的临床效果。最近,有报道称单纯采用骨水泥强化治疗的Kümmell病出现了延迟性骨水泥移位。一些作者建议针对这种特殊情况采用内固定联合骨水泥注射治疗。

目的

评估和比较两种治疗Kümmell病的手术(单纯椎体后凸成形术与短节段固定联合椎体成形术)的临床疗效,尤其是疼痛缓解情况。

研究设计

对术后视觉模拟评分(VAS)和影像学结果进行回顾性评估和比较。

研究地点

单中心住院患者群体。

方法

对54例Kümmell病患者采用两种手术方法,包括传统球囊椎体后凸成形术和短节段固定联合椎体成形术。所有患者均随访8 - 42个月。在术前、术后及末次随访时对两组患者的视觉模拟量表(VAS)、椎体高度和局部后凸角进行评估和比较。计算Pearson相关系数以评估疼痛评分(VAS)降低值与椎体前缘高度及局部后凸角改善之间的关系。

结果

椎体后凸成形术(KP)组,VAS疼痛评分从术前的7.8±0.9显著降至术后的3.3±1.0(P<0.01),末次随访时为2.9±0.9(P<0.01)。椎体前缘平均高度从术前的14.8±2.4mm增加至术后的19.3±2.1mm(P<0.01)。局部平均后凸角从术前的22.7±6.9°降至术后的14.5±5.3°(P<0.01)。短节段固定联合椎体成形术(SSF + VP)组,VAS疼痛评分从术前的7.2±1.6显著降至术后的4.7±1.3(P<0.01),末次随访时为3.5±1.2(P<0.01)。椎体前缘平均高度从术前的13.6±2.5mm增加至术后的17.3±2.7mm(P<0.01)。局部平均后凸角从术前的24.7±9.2°降至术后的15.5±6.2°(P<0.01)。随访期间未观察到椎体高度和后凸畸形矫正的明显丢失。VAS评分的改善与椎体高度或局部后凸角的改善无相关性。两组均出现无症状性骨水泥渗漏。

局限性

样本量相对较小的回顾性研究。

结论

本研究表明,单纯球囊椎体后凸成形术和短节段固定联合椎体成形术治疗Kümmell病均安全有效。VAS评分的改善与椎体高度或局部后凸角的改善无相关性。相比之下,球囊椎体后凸成形术并发症较少,临床效果相当。

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