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经皮椎体后凸成形术是治疗无神经症状的Ⅲ期Kümmell病的更佳选择吗?两种侵入性手术的回顾性研究。

Is Percutaneous Kyphoplasty the Better Choice for Treatment of Stage III Kümmell's Disease Without Neurological Symptoms? A Retrospective Study of Two Invasive Procedures.

作者信息

Liu Yijie, Chen Tangyiheng, Yu Haoyun, Zhou Xiaohui, Hua Runjia, Wang Yudong, Wei Qiang, Gu Yong, Chu Genglei

机构信息

Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Department of Orthopaedic Surgery, The Fourth Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

出版信息

Orthop Surg. 2025 Mar;17(3):724-732. doi: 10.1111/os.14313. Epub 2024 Dec 16.

Abstract

STUDY DESIGN

Retrospective analysis.

OBJECTIVE

Kümmell's disease is an uncommon and complicated spinal condition first described in 1891. Treatment of this disease must be individualized according to the stage of disease and the experience and preference of the surgeon. Nevertheless, the surgical option in Stage III Kümmell's disease without neurological deficits remains controversial. The purpose of this study is to determine whether PKP or pedicle subtraction osteotomy (PSO) combined with long-segment fixation (LSF) is more effective in treating Kümmell's disease at Stage III without neurological impairments.

METHODS

Between January 2017 and June 2020, 89 patients were treated with PKP or PSO + LSF. The outcomes, including operative time, blood loss, Oswestry Disability Indexes (ODIs), heights of fractured vertebrae, visual analog scale (VAS) scores, and kyphosis Cobb angles, were measured at the follow-up time for the PKP group and PSO + LSF group. Fisher's exact test or chi-square test for number and percentage data was employed to compare statistical analyses between two groups.

RESULTS

Forty-six patients underwent PKP and 43 patients who treated by PSO + LSF. Postoperative measurements showed substantial improvements in kyphosis Cobb angle and vertebral height in the PKP group compared to preoperative measurements. Operating time, estimated blood loss, and duration of stay were all reduced in the PKP group compared to the PSO + LSF group. The PSO + LSF group had better correction of a kyphotic Cobb angle than the PKP group. Short-term monitoring showed that the PKP group had fewer ODI and VAS scores than the PSO + LSF group. In addition, no significant neurological symptoms were found after operation in both groups. The complication rates of PKP and PSO + LSF groups were 10.87% and 9.30%, respectively.

CONCLUSIONS

Kümmell's disease in Stage III without neurological symptoms responded to both PKP and PSO + LSF as safe and efficient treatments. Despite limited correction of kyphotic Cobb angle, PKP patients had better early clinical outcomes, increased fractured vertebral height, decreased blood loss, and less surgical trauma compared with the PSO + LSF group.

摘要

研究设计

回顾性分析。

目的

Kümmell病是一种罕见且复杂的脊柱疾病,于1891年首次被描述。该疾病的治疗必须根据疾病阶段以及外科医生的经验和偏好进行个体化。然而,III期无神经功能缺损的Kümmell病的手术选择仍存在争议。本研究的目的是确定椎体后凸成形术(PKP)或经椎弓根截骨术(PSO)联合长节段固定(LSF)在治疗III期无神经功能损害的Kümmell病时哪种方法更有效。

方法

2017年1月至2020年6月期间,89例患者接受了PKP或PSO + LSF治疗。在随访时测量了PKP组和PSO + LSF组的手术时间、失血量、奥斯维斯特残疾指数(ODI)、骨折椎体高度、视觉模拟评分(VAS)以及后凸Cobb角等结果。采用Fisher精确检验或卡方检验对数量和百分比数据进行两组间的统计分析比较。

结果

46例患者接受了PKP治疗,43例患者接受了PSO + LSF治疗。术后测量显示,与术前测量相比,PKP组的后凸Cobb角和椎体高度有显著改善。与PSO + LSF组相比,PKP组的手术时间、估计失血量和住院时间均有所减少。PSO + LSF组在后凸Cobb角的矫正方面优于PKP组。短期监测显示,PKP组的ODI和VAS评分低于PSO + LSF组。此外,两组术后均未发现明显的神经症状。PKP组和PSO + LSF组的并发症发生率分别为10.87%和9.30%。

结论

III期无神经症状的Kümmell病对PKP和PSO + LSF治疗均有反应,且安全有效。尽管PKP组在后凸Cobb角的矫正方面有限,但与PSO + LSF组相比,PKP组患者具有更好的早期临床结果,骨折椎体高度增加,失血量减少,手术创伤更小。

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