Duleba Anna, Skonieczna Katarzyna, Bogdanowicz Wiesław, Malyarchuk Boris, Grzybowski Tomasz
Department of Molecular and Forensic Genetics, Institute of Forensic Medicine, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, 9 Sklodowskiej-Curie Street, 85-094 Bydgoszcz, Poland.
Museum and Institute of Zoology, Polish Academy of Sciences, 64 Wilcza Street, 00-679 Warsaw, Poland.
Forensic Sci Int Genet. 2015 Nov;19:123-129. doi: 10.1016/j.fsigen.2015.06.014. Epub 2015 Jul 17.
To contribute to the complete mitogenome database of the species Canis lupus familiaris and shed more light on its origin, we have sequenced mitochondrial genomes of 120 modern dogs from worldwide populations. Together with all the previously published mitogenome sequences of acceptable quality, we have reconstructed a global phylogenetic tree of 555 C. l. familiaris mitogenomes and standardized haplogroup nomenclature. The phylogenetic tree presented here and available online at http://clf.mtdna.tree.cm.umk.pl/ could be further used by forensic and evolutionary geneticists as well cynologists, for data quality control and unambiguous haplogroup classification. Our in-depth phylogeographic analysis of all C. l. familiaris mitogenomes confirmed that domestic dogs may have originated in East Asia during the Mesolithic and Upper Paleolithic time periods and started to expand to other parts of the world during Neolithic times.
为了丰富家犬物种的完整线粒体基因组数据库，并进一步揭示其起源，我们对来自世界各地种群的120只现代犬的线粒体基因组进行了测序。结合所有之前发表的质量合格的线粒体基因组序列，我们重建了一个包含555个家犬线粒体基因组的全球系统发育树，并规范了单倍型类群命名法。这里展示的以及可在http://clf.mtdna.tree.cm.umk.pl/在线获取的系统发育树，可供法医和进化遗传学家以及犬类学家进一步用于数据质量控制和明确的单倍型类群分类。我们对所有家犬线粒体基因组进行的深入系统地理学分析证实，家犬可能在中石器时代和旧石器时代晚期起源于东亚，并在新石器时代开始向世界其他地区扩张。
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