儿科癌症基因组学：更像戏剧而非画像。
Pediatric cancer genomics, a play rather than a portrait.
机构信息
Division of Haematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
Division of Neurosurgery, Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario, Canada.
出版信息
Nat Genet. 2015 Aug;47(8):851-2. doi: 10.1038/ng.3366.
DOI:10.1038/ng.3366
PMID:26220132
Abstract
Relapsed neuroblastoma is common, frequently lethal and poorly studied and poses a major treatment challenge. Two new studies shed light on the genomic landscape of recurrent neuroblastoma and demonstrate profound differences between the disease at diagnosis and relapse.
摘要
神经母细胞瘤复发很常见，且往往致命，目前研究较少，治疗极具挑战。两项新研究阐明了复发性神经母细胞瘤的基因组图谱，并证实了初诊时与复发时该疾病之间存在显著差异。
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