• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

非小细胞肺癌分期视频纵隔镜检查的质量评估

Quality Assessment of Video Mediastinoscopy Performed for Staging in Non-Small Cell Lung Cancer.

作者信息

Steunenberg Bastiaan, Aerts Bart, De Groot Hans, Boot Conny, Romme Piet, Aerts Joachim, Veen Eelco

机构信息

Department of Surgery, Amphia Hospital, Breda, The Netherlands.

出版信息

Thorac Cardiovasc Surg. 2016 Sep;64(6):520-5. doi: 10.1055/s-0035-1556082. Epub 2015 Jul 28.

DOI:10.1055/s-0035-1556082
PMID:26220697
Abstract

Background Mediastinoscopy is considered to be the gold standard for mediastinal staging for patients with non-small cell lung cancer (NSCLC). The diagnostic value depends on how this procedure is performed, which has resulted in drafting a guideline by the European Society of Thoracic Surgery (ESTS). Biopsy of at least stations 4R, 4L, 7, and if present stations 2R and 2L, is recommended. The objective of this study is to assess the quality of the mediastinoscopies performed in our hospital for NSCLC. Methods Medical records of 102 consecutive patients with suspected or proven NSCLC and a performed cervical mediastinoscopy between January 2009 and November 2014 were analyzed in a retrospective cohort study. The number of biopsied stations and complications has been prospectively documented, together with their clinical data. Results Cervical mediastinoscopy was performed in 102 patients and in 51 (50%) patients biopsy was taken of stations 4R, 4L, and 7. N2/N3 disease emerged more significantly (p < 0.05) if biopsies were taken of at least the paratracheal stations 4R/4L and the subcarinal region. The incidence of major complications was 3.9%. Conclusion In our clinic, 50% of the mediastinoscopies performed are executed following the ESTS guidelines. Our results subscribe the need to biopsy at least the paratracheal stations 4L/4R and the subcarinal region to obtain a reliable assessment of the mediastinum.

摘要

背景

纵隔镜检查被认为是对非小细胞肺癌(NSCLC)患者进行纵隔分期的金标准。其诊断价值取决于该检查的实施方式,这促使欧洲胸外科协会(ESTS)制定了相关指南。建议至少对4R、4L、7区进行活检,若存在2R和2L区也应进行活检。本研究的目的是评估我院对NSCLC患者进行纵隔镜检查的质量。

方法

在一项回顾性队列研究中,分析了2009年1月至2014年11月期间102例连续的疑似或确诊NSCLC且接受了颈部纵隔镜检查患者的病历。前瞻性记录了活检部位数量、并发症及其临床数据。

结果

102例患者接受了颈部纵隔镜检查,其中51例(50%)患者对4R、4L和7区进行了活检。如果至少对气管旁4R/4L区和隆突下区域进行活检,N2/N3疾病的检出更显著(p < 0.05)。主要并发症发生率为3.9%。

结论

在我们的诊所,50%的纵隔镜检查是按照ESTS指南进行的。我们的结果支持至少对气管旁4L/4R区和隆突下区域进行活检以获得可靠纵隔评估的必要性。

相似文献

1
Quality Assessment of Video Mediastinoscopy Performed for Staging in Non-Small Cell Lung Cancer.非小细胞肺癌分期视频纵隔镜检查的质量评估
Thorac Cardiovasc Surg. 2016 Sep;64(6):520-5. doi: 10.1055/s-0035-1556082. Epub 2015 Jul 28.
2
Mediastinoscopy for Staging of Non-Small Cell Lung Cancer: Surgical Performance in The Netherlands.纵隔镜检查在非小细胞肺癌分期中的应用:荷兰的手术表现。
Ann Thorac Surg. 2019 Apr;107(4):1024-1031. doi: 10.1016/j.athoracsur.2018.11.030. Epub 2018 Dec 14.
3
[The biopsying of at least 5 mediastinal lymph node stations for presurgical staging in patients with a non-small-cell lung carcinoma].[对非小细胞肺癌患者进行术前分期时对至少5个纵隔淋巴结站进行活检]
Ned Tijdschr Geneeskd. 2004 Feb 7;148(6):281-6.
4
Endobronchial ultrasound-guided biopsy performed under optimal conditions in patients with known or suspected lung cancer may render mediastinoscopy unnecessary.在已知或疑似肺癌患者中,在最佳条件下进行的支气管内超声引导活检可能使纵隔镜检查变得不必要。
J Bronchology Interv Pulmonol. 2014 Jan;21(1):21-5. doi: 10.1097/LBR.0000000000000028.
5
Endoscopic ultrasound guided biopsy versus mediastinoscopy for analysis of paratracheal and subcarinal lymph nodes in lung cancer staging.超声内镜引导下活检与纵隔镜检查用于肺癌分期中气管旁和隆突下淋巴结分析的比较
Lung Cancer. 2005 Apr;48(1):85-92. doi: 10.1016/j.lungcan.2004.10.002. Epub 2004 Dec 13.
6
The true false negative rates of esophageal and endobronchial ultrasound in the staging of mediastinal lymph nodes in patients with non-small cell lung cancer.超声内镜引导下经支气管针吸活检术诊断非小细胞肺癌纵隔淋巴结转移的假阴性率
Ann Thorac Surg. 2010 Aug;90(2):427-34. doi: 10.1016/j.athoracsur.2010.04.062.
7
Surgical experience and patient-related restrictions predict the adequacy of cervical mediastinoscopy in non-small cell lung carcinoma lymph node staging.手术经验和与患者相关的限制因素可预测非小细胞肺癌淋巴结分期中颈部纵隔镜检查的充分性。
J Cardiothorac Surg. 2018 Dec 29;13(1):134. doi: 10.1186/s13019-018-0821-7.
8
A comparative analysis of video-assisted mediastinoscopy and conventional mediastinoscopy.电视辅助胸腔镜纵隔镜与传统纵隔镜的对比分析。
Ann Thorac Surg. 2011 Sep;92(3):1007-11. doi: 10.1016/j.athoracsur.2011.02.032. Epub 2011 May 20.
9
Guideline adherence of mediastinal staging of non-small cell lung cancer: A multicentre retrospective analysis.纵隔分期非小细胞肺癌指南依从性:多中心回顾性分析。
Lung Cancer. 2019 Aug;134:52-58. doi: 10.1016/j.lungcan.2019.05.031. Epub 2019 May 30.
10
Validity of the updated European Society of Thoracic Surgeons staging guideline in lung cancer patients.更新的欧洲胸外科协会分期指南在肺癌患者中的有效性。
J Thorac Cardiovasc Surg. 2018 Feb;155(2):789-795. doi: 10.1016/j.jtcvs.2017.09.090. Epub 2017 Sep 27.

引用本文的文献

1
Quality indicators in lung cancer: a review and analysis.肺癌的质量指标:综述与分析
BMJ Open Qual. 2021 Aug;10(3). doi: 10.1136/bmjoq-2020-001268.
2
Clinical application of ultrasound-guided mediastinal lymph node biopsy through cervical mediastinoscopy.超声引导经颈纵隔镜纵隔淋巴结活检的临床应用。
Thorac Cancer. 2021 Feb;12(3):297-303. doi: 10.1111/1759-7714.13717. Epub 2020 Nov 3.
3
Preoperative mediastinal staging in patients with cT1-3NxM0 non-small cell lung cancer.cT1-3NxM0 期非小细胞肺癌患者的术前纵隔分期。
Thorac Cancer. 2020 Dec;11(12):3456-3462. doi: 10.1111/1759-7714.13673. Epub 2020 Oct 7.
4
MEDIASTinal staging of non-small cell lung cancer by endobronchial and endoscopic ultrasonography with or without additional surgical mediastinoscopy (MEDIASTrial): study protocol of a multicenter randomised controlled trial.通过支气管内和内镜超声检查联合或不联合额外的手术纵隔镜检查进行非小细胞肺癌的纵隔分期(MEDIAST试验):一项多中心随机对照试验的研究方案
BMC Surg. 2018 May 18;18(1):27. doi: 10.1186/s12893-018-0359-6.