Steunenberg Bastiaan, Aerts Bart, De Groot Hans, Boot Conny, Romme Piet, Aerts Joachim, Veen Eelco
Department of Surgery, Amphia Hospital, Breda, The Netherlands.
Thorac Cardiovasc Surg. 2016 Sep;64(6):520-5. doi: 10.1055/s-0035-1556082. Epub 2015 Jul 28.
Background Mediastinoscopy is considered to be the gold standard for mediastinal staging for patients with non-small cell lung cancer (NSCLC). The diagnostic value depends on how this procedure is performed, which has resulted in drafting a guideline by the European Society of Thoracic Surgery (ESTS). Biopsy of at least stations 4R, 4L, 7, and if present stations 2R and 2L, is recommended. The objective of this study is to assess the quality of the mediastinoscopies performed in our hospital for NSCLC. Methods Medical records of 102 consecutive patients with suspected or proven NSCLC and a performed cervical mediastinoscopy between January 2009 and November 2014 were analyzed in a retrospective cohort study. The number of biopsied stations and complications has been prospectively documented, together with their clinical data. Results Cervical mediastinoscopy was performed in 102 patients and in 51 (50%) patients biopsy was taken of stations 4R, 4L, and 7. N2/N3 disease emerged more significantly (p < 0.05) if biopsies were taken of at least the paratracheal stations 4R/4L and the subcarinal region. The incidence of major complications was 3.9%. Conclusion In our clinic, 50% of the mediastinoscopies performed are executed following the ESTS guidelines. Our results subscribe the need to biopsy at least the paratracheal stations 4L/4R and the subcarinal region to obtain a reliable assessment of the mediastinum.
纵隔镜检查被认为是对非小细胞肺癌(NSCLC)患者进行纵隔分期的金标准。其诊断价值取决于该检查的实施方式,这促使欧洲胸外科协会(ESTS)制定了相关指南。建议至少对4R、4L、7区进行活检,若存在2R和2L区也应进行活检。本研究的目的是评估我院对NSCLC患者进行纵隔镜检查的质量。
在一项回顾性队列研究中,分析了2009年1月至2014年11月期间102例连续的疑似或确诊NSCLC且接受了颈部纵隔镜检查患者的病历。前瞻性记录了活检部位数量、并发症及其临床数据。
102例患者接受了颈部纵隔镜检查,其中51例(50%)患者对4R、4L和7区进行了活检。如果至少对气管旁4R/4L区和隆突下区域进行活检,N2/N3疾病的检出更显著(p < 0.05)。主要并发症发生率为3.9%。
在我们的诊所,50%的纵隔镜检查是按照ESTS指南进行的。我们的结果支持至少对气管旁4L/4R区和隆突下区域进行活检以获得可靠纵隔评估的必要性。