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DNA replication: Strand separation unravelled.

作者信息

Bochman Matthew L, Schwacha Anthony

机构信息

Molecular and Cellular Biochemistry Department, Indiana University, Bloomington, Indiana 47405, USA.

Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

出版信息

Nature. 2015 Aug 13;524(7564):166-7. doi: 10.1038/nature14643. Epub 2015 Jul 29.

DOI:10.1038/nature14643

PMID:26222029

Abstract

摘要

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本文引用的文献

Structure of the eukaryotic MCM complex at 3.8 Å.

Nature. 2015 Aug 13;524(7564):186-91. doi: 10.1038/nature14685. Epub 2015 Jul 29.

How a short double-stranded DNA bends.

J Chem Phys. 2015 Apr 21;142(15):155101. doi: 10.1063/1.4916379.

Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loading.

Cell. 2015 Apr 23;161(3):513-525. doi: 10.1016/j.cell.2015.03.012. Epub 2015 Apr 16.

Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function.

Genes Dev. 2014 Oct 15;28(20):2291-303. doi: 10.1101/gad.242313.114.

Cryo-EM enters a new era.

Elife. 2014 Aug 13;3:e03678. doi: 10.7554/eLife.03678.

Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase.

Cell. 2011 Sep 16;146(6):931-41. doi: 10.1016/j.cell.2011.07.045.

Mechanistic analysis of local ori melting and helicase assembly by the papillomavirus E1 protein.

Mol Cell. 2011 Sep 2;43(5):776-87. doi: 10.1016/j.molcel.2011.06.026.

Origin DNA melting and unwinding in DNA replication.

Curr Opin Struct Biol. 2010 Dec;20(6):756-62. doi: 10.1016/j.sbi.2010.08.009. Epub 2010 Oct 1.

Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.

Mol Cell. 2010 Jan 29;37(2):247-58. doi: 10.1016/j.molcel.2009.12.030.

The Mcm complex: unwinding the mechanism of a replicative helicase.

Microbiol Mol Biol Rev. 2009 Dec;73(4):652-83. doi: 10.1128/MMBR.00019-09.

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相似文献

DNA replication: Strand separation unravelled.

Nature. 2015 Aug 13;524(7564):166-7. doi: 10.1038/nature14643. Epub 2015 Jul 29.

Structure of the eukaryotic MCM complex at 3.8 Å.

Nature. 2015 Aug 13;524(7564):186-91. doi: 10.1038/nature14685. Epub 2015 Jul 29.

Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer.

Nat Struct Mol Biol. 2017 Mar;24(3):300-308. doi: 10.1038/nsmb.3374. Epub 2017 Feb 13.

Unique Roles of the Non-identical MCM Subunits in DNA Replication Licensing.

Mol Cell. 2017 Jul 20;67(2):168-179. doi: 10.1016/j.molcel.2017.06.016.

Cryo-electron microscopy structure of a yeast mitochondrial preprotein translocase.

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Nature. 2015 Feb 19;518(7539):376-80. doi: 10.1038/nature14229. Epub 2015 Feb 4.

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Trends Biochem Sci. 2016 Oct;41(10):859-871. doi: 10.1016/j.tibs.2016.07.011. Epub 2016 Aug 20.

Mechanism and timing of Mcm2-7 ring closure during DNA replication origin licensing.

Nat Struct Mol Biol. 2017 Mar;24(3):309-315. doi: 10.1038/nsmb.3375. Epub 2017 Feb 13.

Architecture of the yeast small subunit processome.

Science. 2017 Jan 13;355(6321). doi: 10.1126/science.aal1880. Epub 2016 Dec 15.

Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate.

Mol Cell Biol. 2015 Jun;35(12):2131-43. doi: 10.1128/MCB.01357-14. Epub 2015 Apr 13.

引用本文的文献

Mechanisms and regulation of DNA replication initiation in eukaryotes.

Crit Rev Biochem Mol Biol. 2017 Apr;52(2):107-144. doi: 10.1080/10409238.2016.1274717. Epub 2017 Jan 17.

Opening the Strands of Replication Origins-Still an Open Question.

Front Mol Biosci. 2016 Sep 30;3:62. doi: 10.3389/fmolb.2016.00062. eCollection 2016.

本文引用的文献

Structure of the eukaryotic MCM complex at 3.8 Å.

Nature. 2015 Aug 13;524(7564):186-91. doi: 10.1038/nature14685. Epub 2015 Jul 29.

How a short double-stranded DNA bends.

J Chem Phys. 2015 Apr 21;142(15):155101. doi: 10.1063/1.4916379.

Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loading.

Cell. 2015 Apr 23;161(3):513-525. doi: 10.1016/j.cell.2015.03.012. Epub 2015 Apr 16.

Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function.

Genes Dev. 2014 Oct 15;28(20):2291-303. doi: 10.1101/gad.242313.114.

Cryo-EM enters a new era.

Elife. 2014 Aug 13;3:e03678. doi: 10.7554/eLife.03678.

Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase.

Cell. 2011 Sep 16;146(6):931-41. doi: 10.1016/j.cell.2011.07.045.

Mechanistic analysis of local ori melting and helicase assembly by the papillomavirus E1 protein.

Mol Cell. 2011 Sep 2;43(5):776-87. doi: 10.1016/j.molcel.2011.06.026.

Origin DNA melting and unwinding in DNA replication.

Curr Opin Struct Biol. 2010 Dec;20(6):756-62. doi: 10.1016/j.sbi.2010.08.009. Epub 2010 Oct 1.

Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.

Mol Cell. 2010 Jan 29;37(2):247-58. doi: 10.1016/j.molcel.2009.12.030.

The Mcm complex: unwinding the mechanism of a replicative helicase.

Microbiol Mol Biol Rev. 2009 Dec;73(4):652-83. doi: 10.1128/MMBR.00019-09.