Cortigiani L, Nutini P, Caiulo V A, Ughi C, Ceccarelli M
Minerva Pediatr. 1989 Nov;41(11):539-42.
Statistically significant lower levels of selenium (p less than 0.001) have been found both in 37 celiac subjects at free diet and in 36 at gluten-free diet with respect to controls. In patients at free diet the deficit of selenium can be attributed to malabsorption, while in patients at gluten-free diet it may be due to the diet itself. Recently low serum levels of selenium have been observed in several neoplasias; furthermore it's known that celiac patients show an increased incidence of gastrointestinal tumors related to known levels in standard population. Long term monitoring is therefore necessary to integrate diet with selenium in patients showing persistent deficit of this element.
在37名自由饮食的乳糜泻患者和36名无麸质饮食的患者中,相对于对照组,均发现了具有统计学意义的较低硒水平(p小于0.001)。在自由饮食的患者中,硒缺乏可归因于吸收不良,而在无麸质饮食的患者中,这可能归因于饮食本身。最近,在几种肿瘤中观察到血清硒水平较低;此外,已知乳糜泻患者胃肠道肿瘤的发病率高于标准人群中的已知水平。因此,对于显示该元素持续缺乏的患者,有必要进行长期监测,以便在饮食中补充硒。