Paolantonio M, Tetè S, Piattelli A, Scaramella F
Minerva Stomatol. 1989 Nov;38(11):1155-60.
Considering the role played by some metabolites of Arachidonic Acid in the pathogenesis of periodontal disease, the Authors have investigated on the existence of a relation between the Thromboxane B2 concentration in gingival tissues and the principal clinical Indices of periodontal health: Gingival Index, Plaque Index, pocket depth, and Bleeding Time Index. The results showed that just the bleeding Index resulted to be well related to the Thromboxane B2 tissue concentration and then to the level of inflammation of deep periodontal tissues. On the ground of these data the Authors underline the importance held by the bleeding index in the showing to the Clinician the therapy necessity of a periodontal site in order to prevent a possible future attachment loss.
考虑到花生四烯酸的某些代谢产物在牙周病发病机制中所起的作用，作者研究了牙龈组织中血栓素B2浓度与牙周健康主要临床指标之间的关系：牙龈指数、菌斑指数、牙周袋深度和出血时间指数。结果表明，只有出血指数与血栓素B2组织浓度以及深部牙周组织的炎症水平密切相关。基于这些数据，作者强调出血指数对于向临床医生表明牙周部位治疗必要性的重要性，以防止未来可能发生的附着丧失。
