Mannion Anne F, Impellizzeri Franco M, Naal Florian D, Leunig Michael
Department of Research and Development, Schulthess Clinic, Lengghalde 2, Zurich, 8008, Switzerland.
Department of Orthopaedic Surgery, Schulthess Clinic, Zurich, Switzerland.
Clin Orthop Relat Res. 2015 Dec;473(12):3849-57. doi: 10.1007/s11999-015-4479-3.
Many studies report differences in patient-reported outcome measures (PROMs) for men and women undergoing total hip arthroplasty (THA). Few studies have evaluated whether these are explained by corresponding differences in important preoperative factors.
QUESTIONS/PURPOSES: (1) Are there differences between men and women in PROM scores preoperatively and 12 months after THA? (2) Do baseline differences in comorbidity, age, body mass index (BMI), and mental health status explain these differences in PROM scores?
Preoperatively, 300 patients completed the Oxford Hip Score (OHS), WOMAC, and SF-12; 261 (86%) of them (129 women, 64 ± 11 years; 132 men, 66 ± 10 years) completed the same questionnaires 12 months postoperatively and also rated the acceptability of their current symptoms and change in general health.
Preoperatively, women showed worse scores than men in the OHS (-1.9; 95% confidence interval, -3.6 to -0.3) and WOMAC (-6.3; -10.9 to -1.7). At 12 months postoperatively, the absolute scores for all PROMs were not significantly different. After controlling for BMI, age, comorbidity, SF-12 mental health scores, and sociodemographic characteristics, the baseline differences remained.
Surgeons may be more reluctant to operate on women than men because they perceive that, because of their worse baseline status, women are likely to have worse outcomes; however, given that we found no evidence for differences in patient-reported outcomes at 12 months, these suspicions would appear to be unfounded. Women and men can be expected to benefit to a similar extent from THA.
Level III, therapeutic study.
许多研究报告了接受全髋关节置换术(THA)的男性和女性在患者报告结局指标(PROMs)上的差异。很少有研究评估这些差异是否可以由重要术前因素的相应差异来解释。
问题/目的:(1)男性和女性在THA术前及术后12个月的PROM评分是否存在差异?(2)合并症、年龄、体重指数(BMI)和心理健康状况的基线差异是否能解释PROM评分的这些差异?
术前,300名患者完成了牛津髋关节评分(OHS)、WOMAC和SF - 12;其中261名(86%)患者(129名女性,64±11岁;132名男性,66±10岁)在术后12个月完成了相同问卷,并对其当前症状的可接受性和总体健康变化进行了评分。
术前,女性在OHS(-1.9;95%置信区间,-3.6至-0.3)和WOMAC(-6.3;-10.9至-1.7)评分上比男性差。术后12个月,所有PROM的绝对评分无显著差异。在控制了BMI、年龄、合并症、SF - 12心理健康评分和社会人口统计学特征后,基线差异仍然存在。
外科医生可能比男性更不愿意为女性做手术,因为他们认为,由于女性基线状态较差,其预后可能更差;然而,鉴于我们没有发现12个月时患者报告结局存在差异的证据,这些怀疑似乎没有根据。可以预期,男性和女性从THA中获益的程度相似。
III级,治疗性研究。