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本文引用的文献

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Efficient Detection of Carbapenemase Activity in Enterobacteriaceae by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry in Less Than 30 Minutes.基质辅助激光解吸电离飞行时间质谱法在30分钟内高效检测肠杆菌科细菌中的碳青霉烯酶活性
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Evaluation of five chromogenic agar media and the Rosco Rapid Carb screen kit for detection and confirmation of carbapenemase production in Gram-negative bacilli.评估五种显色琼脂培养基和罗斯科快速碳水化合物筛选试剂盒用于检测和确认革兰氏阴性杆菌中产碳青霉烯酶的情况。
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French regional surveillance program of carbapenemase-producing Gram-negative bacilli: results from a 2-year period.法国产碳青霉烯酶革兰氏阴性杆菌区域监测项目：两年期结果
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4
Incidence rates of carbapenemase-producing Enterobacteriaceae clinical isolates in France: a prospective nationwide study in 2011-12.法国产碳青霉烯酶肠杆菌科临床分离株的发病率：2011 - 2012年全国前瞻性研究。
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Long-term control of carbapenemase-producing Enterobacteriaceae at the scale of a large French multihospital institution: a nine-year experience, France, 2004 to 2012.法国一家大型多医院机构 2004 年至 2012 年 9 年时间产碳青霉烯酶肠杆菌科细菌的长期控制：一项经验
Euro Surveill. 2014 May 15;19(19):20802. doi: 10.2807/1560-7917.es2014.19.19.20802.
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Antibiotic resistance-the need for global solutions.抗生素耐药性——全球解决方案的必要性。
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A disc diffusion assay for detection of class A, B and OXA-48 carbapenemases in Enterobacteriaceae using phenyl boronic acid, dipicolinic acid and temocillin.采用苯硼酸、二吡啶酸和替莫西林检测肠杆菌科中 A、B 和 OXA-48 碳青霉烯酶的纸片扩散法。
Clin Microbiol Infect. 2014 Apr;20(4):345-9. doi: 10.1111/1469-0691.12322. Epub 2013 Aug 9.
8
Carbapenemase-producing Enterobacteriaceae in Europe: a survey among national experts from 39 countries, February 2013.欧洲产碳青霉烯酶肠杆菌科细菌：39 个国家国家专家调查，2013 年 2 月。
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9
Virulence of Klebsiella pneumoniae isolates harboring bla KPC-2 carbapenemase gene in a Caenorhabditis elegans model.携带 bla KPC-2 碳青霉烯酶基因的肺炎克雷伯菌分离株在秀丽隐杆线虫模型中的毒力。
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Temocillin and meropenem to discriminate resistance mechanisms leading to decreased carbapenem susceptibility with focus on OXA-48 in Enterobacteriaceae.替莫西林和美罗培南用于区分导致肠杆菌科对碳青霉烯类药物敏感性降低的耐药机制，重点关注 OXA-48。
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两种用于产碳青霉烯酶肠杆菌科细菌的表型筛选试验的评估

Evaluation of Two Phenotypic Screening Tests for Carbapenemase-Producing Enterobacteriaceae.

作者信息

Pantel Alix, Souzy Dimitri, Sotto Albert, Lavigne Jean-Philippe

机构信息

Institut National de la Santé et de la Recherche Médicale, Université de Montpellier, UFR de Médecine, Nîmes, France Laboratoire de Bactériologie, CHU Carémeau, Nîmes University Hospital, Nîmes, France.

Laboratoire de Bactériologie, CHU Carémeau, Nîmes University Hospital, Nîmes, France.

出版信息

J Clin Microbiol. 2015 Oct;53(10):3359-62. doi: 10.1128/JCM.01211-15. Epub 2015 Jul 29.

DOI:10.1128/JCM.01211-15
PMID:26224841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4572552/
Abstract

We evaluated the performance of two rapid tests for detection of carbapenemase-producing Enterobacteriaceae (CPE) strains. The sensitivities and the specificities were 97.6% and 94.4% for the Rapid CARB Screen and 98.8% and 93.1% for the KPC/MBL & OXA-48 Confirm tests, providing the usefulness of these tools for screening CPE in microbiology wards.

摘要

我们评估了两种用于检测产碳青霉烯酶肠杆菌科（CPE）菌株的快速检测方法的性能。快速碳青霉烯筛查试验的敏感性和特异性分别为97.6%和94.4%，KPC/MBL和OXA - 48确认试验的敏感性和特异性分别为98.8%和93.1%，这表明这些工具在微生物病房筛查CPE方面具有实用性。