Al-Nuzal S M D, Al-Azzawi H M A-K, Al-Mosawy Z M J
Environmental Research Centre, The University of Technology, Baghdad, Iraq.
Directorate of Chemistry and Petrochemical Industry, Ministry of Science and Technology, Al-Jadiryia, Baghdad, Iraq.
J Radioanal Nucl Chem. 2013;295(3):1599-1604. doi: 10.1007/s10967-012-2356-z. Epub 2012 Dec 11.
A new method to prepare novel semi-rigid multidentate ligands containing nitrogen atom, to coordinate with rhenium and technetium, was established. The method was based on formylation of substituted anilines, followed by Mannich reaction with glycine and paraformaldehyde. The method was very promising to design ligands of various molecular structures (L-L) to coordinate with rhenium metal ions. The complexes were prepared through ligand exchange with the complex ReOCl(PPh), giving new complex of the structure ReOClL. The prepared ligands and complexes were identified by the use of UV-vis, and infrared absorption spectrometric techniques, elemental analysis, molecular weight determination by depression of freezing point. These ligands were labeled with Tc pertechnetate, and the labeling efficiency of the complexes was measured using a well type scintillation gamma counter equipment and obtained a good yield.
建立了一种制备含氮新型半刚性多齿配体以与铼和锝配位的新方法。该方法基于取代苯胺的甲酰化反应，然后与甘氨酸和多聚甲醛进行曼尼希反应。该方法对于设计各种分子结构（L-L）的配体以与铼金属离子配位非常有前景。通过与配合物ReOCl(PPh)进行配体交换制备配合物，得到结构为ReOClL的新配合物。通过紫外可见光谱、红外吸收光谱技术、元素分析、凝固点降低法测定分子量等方法对制备的配体和配合物进行了鉴定。这些配体用高锝酸盐进行标记，并使用井型闪烁伽马计数器设备测量配合物的标记效率，获得了良好的产率。
