Chan Fung M, Galatioto Jessica, Amato Michael, Kim Ana H
Department of Otolaryngology, New York Eye and Ear Infirmary of Mount Sinai, New York, U.S.A.
New York Medical College, Valhalla, New York, U.S.A.
Laryngoscope. 2016 Feb;126(2):460-3. doi: 10.1002/lary.25497. Epub 2015 Jul 30.
OBJECTIVES/HYPOTHESIS: The purpose of this study is to examine the range of vestibulo-ocular reflex (VOR) gain on rotary chair (RC) testing in subjects without ear and vestibular problems stratified by age and gender.
Prospective cross-sectional study.
One hundred subjects ranging in age from 6 to 78 years underwent RC testing. VOR gains at frequencies ranging from 0.01 to 0.64 Hz were recorded. The PROC MIXED procedure in SAS was used to analyze differences in VOR gain between gender and the following age groups: group 1 (6-12 years), group 2 (13-17 years), group 3 (18-30 years), group 4 (31-50 years), and group 5 (>50 years).
Twenty subjects were recruited for each of the five groups. Group 1 showed the highest average VOR gain compared to all other age groups (P < .05). There was an inverse correlation between VOR gain and age (P < .05). The lowest frequency (0.01 Hz) had the highest correlation between VOR gain and age (r = -0.425; P < .0001).
Our study demonstrates VOR gain differences with age, especially in the preadolescent and geriatric groups. The current manufacturer-provided normative data do not serve as an accurate reference, especially for these two age groups. A larger population of all age groups should be compared to the current RC manufacturer normative values to ensure that they accurately reflect the true normative data.
目的/假设:本研究的目的是在无耳部和前庭问题的受试者中,按年龄和性别分层,检查旋转椅(RC)测试中的前庭眼反射(VOR)增益范围。
前瞻性横断面研究。
100名年龄在6至78岁之间的受试者接受了RC测试。记录了频率范围为0.01至0.64Hz时的VOR增益。使用SAS中的PROC MIXED程序分析性别和以下年龄组之间VOR增益的差异:第1组(6 - 12岁)、第2组(13 - 17岁)、第3组(18 - 30岁)、第4组(31 - 50岁)和第5组(>50岁)。
五个组每组招募了20名受试者。与所有其他年龄组相比,第1组显示出最高的平均VOR增益(P <.05)。VOR增益与年龄呈负相关(P <.05)。最低频率(0.01Hz)时,VOR增益与年龄之间的相关性最高(r = -0.425;P <.0001)。
我们的研究表明VOR增益随年龄存在差异,尤其是在青春期前和老年组。当前制造商提供的标准数据不能作为准确的参考,特别是对于这两个年龄组。应该将更多不同年龄组的人群与当前RC制造商的标准值进行比较,以确保它们准确反映真实的标准数据。
2级。