Hanson J M, Goebel J A
Department of Otolaryngology-Head and Neck Surgery, Washington University, School of Medicine, Saint Louis, Missouri, USA.
J Vestib Res. 1998 May-Jun;8(3):273-82.
New methods of rotational testing of the vestibulo-ocular reflex (VOR) using manually generated or patient-generated sinusoidal head movements have recently been advocated for clinical use in circumstances where conventional rotary chair testing methods are not feasible. However, studies seeking to provide evidence for the validity of these methods by comparing their results with an accepted "gold-standard" have been conspicuously absent in the literature. In this study, we compared results for VOR gain, phase, and asymmetry obtained using whole-body and head-on-body rotational stimuli with those obtained by conventional rotary chair testing in 35 subjects with either unilateral or bilateral vestibular deficits over the range of frequencies from 0.025 Hz to 1 Hz. Our results provide evidence for the validity of manual whole-body and active and passive head-on-body rotational testing methods by demonstrating excellent agreement between each of these and conventional rotational chair testing for VOR gain, phase, and asymmetry within the frequency range studied. Small differences at specific-paradigm datapoints are likely secondary to subtle limitations of our experimental design. With further refinement, we expect the new methods will be useful adjuncts for evaluating patients with vestibular complaints in selected clinical situations.
最近有人提倡使用手动生成或患者生成的正弦头部运动来进行前庭眼反射（VOR）旋转测试的新方法，以便在传统转椅测试方法不可行的情况下用于临床。然而，文献中明显缺乏通过将这些方法的结果与公认的“金标准”进行比较来为其有效性提供证据的研究。在本研究中，我们比较了35名单侧或双侧前庭功能缺损受试者在0.025 Hz至1 Hz频率范围内使用全身和头在身体上的旋转刺激获得的VOR增益、相位和不对称性结果与传统转椅测试获得的结果。我们的结果通过证明在所研究的频率范围内，这些方法中的每一种与传统转椅测试在VOR增益、相位和不对称性方面具有极好的一致性，为手动全身以及主动和被动头在身体上的旋转测试方法的有效性提供了证据。特定范式数据点的小差异可能是由于我们实验设计的细微局限性所致。随着进一步完善，我们预计这些新方法将成为在选定临床情况下评估前庭功能障碍患者的有用辅助手段。
