Lin Zhijing, Zhao Zhuohui, Xu Huihui, Zhang Xin, Wang Tingting, Kan Haidong, Norback Dan
Department of Environmental Health, School of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai, 200032, P. R. China.
Department of Environmental Health, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, 200032, China.
PLoS One. 2015 Jul 31;10(7):e0134359. doi: 10.1371/journal.pone.0134359. eCollection 2015.
There is an increasing prevalence of childhood asthma and allergic diseases in mainland of China. Few studies investigated the indoor dampness, ventilation and cleaning habits and their interrelationship with childhood asthma and allergic diseases. A large-scale cross-sectional study was performed in preschool children in Urumqi, China. Questionnaire was used to collect information on children's health, home dampness and ventilation/cleaning (V/C) habits. Multiple logistic regressions were applied to analyze the associations between childhood asthma/allergic diseases and each sign of home dampness, dampness levels, each V/C habit and total V/C scores. The associations between dampness and health were further performed by strata analyses in two groups with low and high V/C scores. Totally 4618(81.7%) of 5650 children returned the questionnaire. Reports on home dampness were most common for water condensation on windows (20.8%) followed by damp beddings (18.0%). The most common ventilation measure was the use of exhaust fan in bathroom (59.3%), followed by daily home cleaning (48.3%), frequently putting beddings to sunshine (29.9%) and frequently opening windows in winter (8.4%). There were positive associations between the 6 signs of home dampness and children's health particularly the symptoms last 12 months. By comparing with the reference dampness level (dampness scored 0), both the low dampness (scored 12) level and the high dampness level (scored 36) showed significantly increasing associations with childhood symptoms. There were crude negative associations between V/C habits and childhood health but not significant adjusting for home dampness levels. The risks of home dampness on children's health were lower in the group with higher V/C score but the differences were not statistically significant. Home dampness is a potential risk factor for childhood asthma and allergic symptoms in preschool children in Urumqi, China. No significant effects were observed for ordinary home ventilation and cleaning habits in reducing the risks of home dampness on childhood asthma and allergic diseases in Urumqi, China.
中国内地儿童哮喘和过敏性疾病的患病率呈上升趋势。很少有研究调查室内潮湿、通风和清洁习惯及其与儿童哮喘和过敏性疾病的相互关系。在中国乌鲁木齐对学龄前儿童进行了一项大规模横断面研究。采用问卷调查收集儿童健康、家庭潮湿及通风/清洁(V/C)习惯等信息。应用多因素logistic回归分析儿童哮喘/过敏性疾病与家庭潮湿的各项指标、潮湿程度、每种V/C习惯及V/C总分之间的关联。通过对V/C得分低和高的两组进行分层分析,进一步研究潮湿与健康之间的关联。5650名儿童中共有4618名(81.7%)返回了问卷。家庭潮湿报告中最常见的是窗户上有水珠(20.8%),其次是被褥潮湿(18.0%)。最常见的通风措施是在浴室使用排气扇(59.3%),其次是每日家庭清洁(48.3%)、经常将被褥晒太阳(29.9%)和冬季经常开窗(8.4%)。家庭潮湿的6项指标与儿童健康呈正相关,尤其是过去12个月的症状。与参考潮湿水平(潮湿评分为0)相比,低潮湿水平(评分为12)和高潮湿水平(评分为36)均与儿童症状呈显著增加的关联。V/C习惯与儿童健康之间存在粗略的负相关,但在调整家庭潮湿水平后无显著意义。V/C得分较高组中家庭潮湿对儿童健康的风险较低,但差异无统计学意义。家庭潮湿是中国乌鲁木齐学龄前儿童患儿童哮喘和过敏症状的潜在危险因素。在中国乌鲁木齐,普通的家庭通风和清洁习惯在降低家庭潮湿对儿童哮喘和过敏性疾病的风险方面未观察到显著效果。