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[多发性肌炎综合征的免疫学研究]

[Immunologic studies in polymyositis syndromes].

作者信息

Oehninger C, Rodríguez T, Passano R, Casanova E, Paciel J, Lasalvia E

出版信息

Acta Neurol Latinoam. 1979;25(3-4):249-69.

PMID:262355
Abstract

Sixteen cases of polymyositis were submitted to study. Out of these sixteen, nine showed no clinical or paraclinical evidences of cancer, and seven presented an associated cancer. In the first group, a normal immune response was observed, whereas in the second group this response was frankly depressed. Emphasis is laid on the significance of the immune response, not only in the diagnosis but as a fundamental factor in prognosis and treatment as well. An early treatment of polymyositis without cancer proved to be satisfactory. On the other hand, when a neoplasm was present, the course of the disease was satisfactorily modified only after the extirpation of the neoplasm.

摘要

对16例多发性肌炎患者进行了研究。在这16例患者中,9例未显示出癌症的临床或副临床证据,7例伴有癌症。在第一组中,观察到免疫反应正常,而在第二组中,这种反应明显受到抑制。重点强调免疫反应的重要性,不仅在诊断中,而且在预后和治疗中也是一个基本因素。事实证明,早期治疗无癌症的多发性肌炎效果令人满意。另一方面,当存在肿瘤时,只有在切除肿瘤后,疾病进程才得到令人满意的改善。

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