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重复腰椎穿刺:脑脊液乳酸水平可预测急性细菌性脑膜炎的治愈情况。

Repeat Lumbar Puncture: CSF Lactic Acid Levels are Predictive of Cure with Acute Bacterial Meningitis.

作者信息

Cunha Burke A

机构信息

Infectious Disease Division, Winthrop-University Hospital, Mineola, NY 11501, USA.

School of Medicine, State University of New York, Stony Brook New York, NY 11501, USA .

出版信息

J Clin Med. 2013 Dec 17;2(4):328-30. doi: 10.3390/jcm2040328.

Abstract

A common clinical problem concerns the utility of repeat lumbar puncture (LP) in adults with acute bacterial meningitis (ABM), e.g., pneumococcal meningitis [1]. An LP is initially done for diagnostic purposes in patients with suspected ABM, i.e., diagnostic lumbar puncture (DLP). A repeat LP (RLP) may be done 1-3 days after the initial DLP, if the patient shows no improvement. If a patient with ABM is not doing well after three days, adequacy of antimicrobial therapy is the main concern. Other reasons for RLP is to detect possible intracranial complications of ABM unrelated to adequacy of therapy [1-2].

摘要

一个常见的临床问题涉及重复腰椎穿刺(LP)在患有急性细菌性脑膜炎(ABM)的成人中的效用,例如肺炎球菌性脑膜炎[1]。对于疑似ABM的患者,最初进行LP是为了诊断目的,即诊断性腰椎穿刺(DLP)。如果患者没有改善,可在初次DLP后1 - 3天进行重复LP(RLP)。如果ABM患者在三天后病情没有好转,抗菌治疗的充分性是主要关注点。RLP的其他原因是检测与治疗充分性无关的ABM可能的颅内并发症[1 - 2]。

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本文引用的文献

1
The clinical and laboratory diagnosis of acute meningitis and acute encephalitis.急性脑膜炎和急性脑炎的临床与实验室诊断
Expert Opin Med Diagn. 2013 Jul;7(4):343-64. doi: 10.1517/17530059.2013.804508. Epub 2013 May 30.
7
The dilemma of partially treated bacterial meningitis.部分治疗的细菌性脑膜炎的困境
Scand J Infect Dis. 1976;8(3):185-8. doi: 10.3109/inf.1976.8.issue-3.12.

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