Mittal Ruchi, Thumann Gabrielle, Souteyrand George, Kuerten David, Coupland Sarah E
Dalmia Ophthalmic Pathology Services, L.V. Prasad Eye Institute, Bhubaneswar, India,
J Ophthalmic Inflamm Infect. 2015 Dec;5(1):55. doi: 10.1186/s12348-015-0055-y. Epub 2015 Aug 4.
Toxoplasmosis is a relatively rare complication in renal transplant patients and can pose diagnostic challenges, especially when it manifests as an ocular inflammation. Authors hereby report an unusual case of a 57-year-old male who developed retinochoroidal toxoplasmosis after 15 years of renal transplant, the diagnoses of which were challenging as the patient was also a known case of cerebral post-transplant lymphoproliferative disease (PTLD) of Hodgkin's type, which misled the ophthalmologists towards a clinical diagnosis of ocular PTLD. Histopathology examination of the enucleated eye revealed numerous toxoplasmosis cysts within the retina and choroid. No ocular PTLD was observed.
弓形虫病在肾移植患者中是一种相对罕见的并发症,可能带来诊断挑战,尤其是当它表现为眼部炎症时。作者在此报告一例不寻常病例,一名57岁男性在肾移植15年后发生视网膜脉络膜弓形虫病,由于该患者也是已知的霍奇金型移植后脑淋巴组织增生性疾病(PTLD)病例,这误导了眼科医生对眼部PTLD的临床诊断,因此该病例的诊断颇具挑战性。摘除眼球的组织病理学检查显示视网膜和脉络膜内有大量弓形虫囊肿。未观察到眼部PTLD。