Smoczyński Marian, Jagielski Mateusz, Jabłońska Anna, Adrych Krystian
Department of Gastroenterology and Hepatology, Medical University of Gdansk, Gdansk, Poland.
Wideochir Inne Tech Maloinwazyjne. 2015 Jul;10(2):237-43. doi: 10.5114/wiitm.2015.52058. Epub 2015 Jun 9.
Our report presents a technique of necrotic tissue removal during transmural drainage of walled-off pancreatic necrosis (WOPN) that is an alternative to the one that has already been described in the literature.
To assess the effectiveness and safety of endoscopic necrosectomy performed during transmural drainage of symptomatic WOPN.
Within the years 2012-2013, 64 patients underwent endoscopic treatment of symptomatic WOPN in our center. Eight patients underwent endoscopic necrosectomy during transmural drainage. Fragments of necrotic tissues were removed from the collection's cavity under fluoroscopic guidance using a Dormia basket. The results and complications of treatment were compared retrospectively.
Sixty-four patients with WOPN underwent transmural drainage under endoscopic ultrasonography (EUS) guidance. Eight patients (12.5%, 5 women and 3 men, mean age 57.25 years) were qualified for endoscopic necrosectomy. Transmural transgastric access was made in 7 patients and transduodenal access in 1 patient. Additional percutaneous drainage was used in 2 patients. Active drainage was continued for 24 days (11-44 days). The mean number of endoscopic procedures was 4.75 (3-9). The average number of necrosectomy procedures during drainage was 1.75 (1-4). Complications of endotherapy occurred in 2/8 (25%) patients, and they were not directly connected with necrosectomy. Therapeutic success after the end of active drainage was achieved in all patients. During a 6-month follow-up no recurrence of the collection was observed.
Endoscopic necrosectomy under fluoroscopic guidance is an effective and safe method of minimally invasive treatment in a selected group of patients with symptomatic WOPN.
我们的报告介绍了一种在壁性坏死性胰腺炎(WOPN)经壁引流过程中清除坏死组织的技术,该技术是文献中已描述技术的一种替代方法。
评估有症状的WOPN经壁引流期间进行内镜下坏死组织清除术的有效性和安全性。
2012年至2013年期间,我们中心有64例患者接受了有症状WOPN的内镜治疗。8例患者在经壁引流期间接受了内镜下坏死组织清除术。在荧光透视引导下,使用多尔米亚篮从积液腔中清除坏死组织碎片。对治疗结果和并发症进行回顾性比较。
64例WOPN患者在内镜超声(EUS)引导下接受了经壁引流。8例患者(12.5%,5名女性和3名男性,平均年龄57.25岁)符合内镜下坏死组织清除术的条件。7例患者采用经壁经胃途径,1例患者采用经十二指肠途径。2例患者使用了额外的经皮引流。持续主动引流24天(11 - 44天)。内镜手术的平均次数为4.75(3 - 9次)。引流期间坏死组织清除术的平均次数为1.75(1 - 4次)。2/8(25%)的患者发生了内镜治疗并发症,且这些并发症与坏死组织清除术无直接关联。所有患者在主动引流结束后均取得了治疗成功。在6个月的随访期间,未观察到积液复发。
荧光透视引导下的内镜下坏死组织清除术是治疗部分有症状WOPN患者的一种有效且安全的微创方法。