The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, United Kingdom; email:
Annu Rev Phytopathol. 2015;53:379-402. doi: 10.1146/annurev-phyto-080614-120347.
A significant challenge for plants is to induce localized defense responses at sites of pathogen attack. Therefore, host subcellular trafficking processes enable accumulation and exchange of defense compounds, which contributes to the plant on-site defenses in response to pathogen perception. This review summarizes our current understanding of the transport processes that facilitate immunity, the significance of which is highlighted by pathogens reprogramming membrane trafficking through host cell translocated effectors. Prominent immune-related cargos of plant trafficking pathways are the pattern recognition receptors (PRRs), which must be present at the plasma membrane to sense microbes in the apoplast. We focus on the dynamic localization of the FLS2 receptor and discuss the pathways that regulate receptor transport within the cell and their link to FLS2-mediated immunity. One emerging theme is that ligand-induced late endocytic trafficking is conserved across different PRR protein families as well as across different plant species.
植物面临的一个重大挑战是在病原体攻击部位诱导局部防御反应。因此，宿主亚细胞运输过程能够积累和交换防御化合物，这有助于植物对病原体感知做出原位防御。本综述总结了我们对促进免疫的运输过程的理解，病原体通过宿主细胞易位效应子重新编程膜运输，凸显了这一过程的重要性。植物运输途径中突出的免疫相关货物是模式识别受体 (PRR)，它们必须存在于质膜上才能感应质外体中的微生物。我们重点研究了 FLS2 受体的动态定位，并讨论了调节细胞内受体运输的途径及其与 FLS2 介导的免疫的联系。一个新兴主题是，配体诱导的晚期内吞运输在不同的 PRR 蛋白家族以及不同的植物物种中是保守的。
