Dhaliwal Ruban, Weinstock Ruth S
Diabetes Spectr. 2014 Feb;27(1):9-20. doi: 10.2337/diaspect.27.1.9.
Older adults with type 1 diabetes are at high risk for severe hypoglycemia and may have serious comorbid conditions. Problems with cognition, mobility, dexterity, vision, hearing, depression, and chronic pain interfere with the ability to follow complex insulin regimens. With the development of geriatric syndromes, unpredictable eating, and frailty, treatment regimens must be modified with the goal of minimizing hypoglycemia and severe hyperglycemia and maximizing quality of life.
1型糖尿病老年患者发生严重低血糖的风险很高,且可能伴有严重的合并症。认知、行动能力、灵活性、视力、听力、抑郁和慢性疼痛等问题会干扰遵循复杂胰岛素治疗方案的能力。随着老年综合征、不可预测的饮食和虚弱状况的出现,必须调整治疗方案,目标是将低血糖和严重高血糖降至最低,并将生活质量最大化。