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非危重症住院患者高血糖的药物治疗

Pharmacotherapy for Hyperglycemia in Noncritically Ill Hospitalized Patients.

作者信息

Mendez Carlos E, Umpierrez Guillermo E

出版信息

Diabetes Spectr. 2014 Aug;27(3):180-8. doi: 10.2337/diaspect.27.3.180.

DOI:10.2337/diaspect.27.3.180
PMID:26246777
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4523735/
Abstract

In Brief Hyperglycemia in the hospital setting affects 38-46% of noncritically ill hospitalized patients. Evidence from observational studies indicates that inpatient hyperglycemia, in patients with and without diabetes, is associated with increased risks of complications and mortality. Substantial evidence indicates that correction of hyperglycemia through insulin administration reduces hospital complications and mortality in critically ill patients, as well as in general medicine and surgery patients. This article provides a review of the evidence on the different therapies available for hyperglycemia management in noncritically ill hospitalized patients.

摘要

简而言之,医院环境中的高血糖影响38%-46%的非危重症住院患者。观察性研究的证据表明,无论有无糖尿病,住院患者的高血糖都与并发症和死亡风险增加相关。大量证据表明,通过胰岛素给药纠正高血糖可降低危重症患者以及普通内科和外科患者的医院并发症和死亡率。本文综述了非危重症住院患者高血糖管理可用的不同治疗方法的证据。

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本文引用的文献

1
Metformin-associated lactic acidosis.二甲双胍相关性乳酸酸中毒
Am J Med Sci. 2015 Mar;349(3):263-7. doi: 10.1097/MAJ.0b013e3182a562b7.
2
The glucoregulatory benefits of glucagon-like peptide-1 (7-36) amide infusion during intensive insulin therapy in critically ill surgical patients: a pilot study.在危重症外科患者强化胰岛素治疗期间输注胰高血糖素样肽-1(7-36)酰胺的糖调节益处:一项初步研究。
Crit Care Med. 2014 Mar;42(3):638-45. doi: 10.1097/CCM.0000000000000035.
3
Increased glycemic variability is independently associated with length of stay and mortality in noncritically ill hospitalized patients.血糖变异性增加与非危重症住院患者的住院时间和死亡率独立相关。
Diabetes Care. 2013 Dec;36(12):4091-7. doi: 10.2337/dc12-2430. Epub 2013 Oct 29.
4
Intravenous GLP-1 (7-36) amide for prevention of hyperglycemia during cardiac surgery: a randomized, double-blind, placebo-controlled study.静脉注射胰高血糖素样肽-1(7-36)酰胺预防心脏手术期间高血糖:一项随机、双盲、安慰剂对照研究。
J Cardiothorac Vasc Anesth. 2014 Jun;28(3):618-25. doi: 10.1053/j.jvca.2013.06.021. Epub 2013 Oct 19.
5
K(ATP) channels and islet hormone secretion: new insights and controversies.K(ATP) 通道与胰岛激素分泌:新的认识与争议。
Nat Rev Endocrinol. 2013 Nov;9(11):660-9. doi: 10.1038/nrendo.2013.166. Epub 2013 Sep 17.
6
Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysis.钠-葡萄糖共转运蛋白 2 抑制剂治疗 2 型糖尿病:系统评价和荟萃分析。
Ann Intern Med. 2013 Aug 20;159(4):262-74. doi: 10.7326/0003-4819-159-4-201308200-00007.
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Glucose variability is an independent predictor of mortality in hospitalized patients treated with total parenteral nutrition.血糖变异性是接受全胃肠外营养治疗的住院患者死亡率的独立预测因素。
Endocr Pract. 2014 Jan;20(1):41-5. doi: 10.4158/EP13131.OR.
8
Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus.沙格列汀与 2 型糖尿病患者的心血管结局。
N Engl J Med. 2013 Oct 3;369(14):1317-26. doi: 10.1056/NEJMoa1307684. Epub 2013 Sep 2.
9
Safety and efficacy of sitagliptin therapy for the inpatient management of general medicine and surgery patients with type 2 diabetes: a pilot, randomized, controlled study.西他列汀治疗2型糖尿病普通内科和外科住院患者的安全性和有效性:一项前瞻性、随机、对照研究。
Diabetes Care. 2013 Nov;36(11):3430-5. doi: 10.2337/dc13-0277. Epub 2013 Jul 22.
10
Is incretin-based therapy ready for the care of hospitalized patients with type 2 diabetes?: Insulin therapy has proven itself and is considered the mainstay of treatment.基于肠促胰岛素的治疗是否已准备好用于住院 2 型糖尿病患者的治疗?:胰岛素治疗已被证明有效,被认为是治疗的主要手段。
Diabetes Care. 2013 Jul;36(7):2112-7. doi: 10.2337/dc12-2233.