Knatz Stephanie, Wierenga Christina E, Murray Stuart B, Hill Laura, Kaye Walter H
University of California San Diego, Department of Psychiatry, San Diego, California, USA.
Ohio State University, Department of Psychiatry, Columbus, Ohio, USA.
Dialogues Clin Neurosci. 2015 Jun;17(2):229-36. doi: 10.31887/DCNS.2015.17.2/sknatz.
Anorexia nervosa (AN) is a severe and debilitating disorder with significant medical and psychological sequelae. To date, there are no effective treatments for adults, resulting in high rates of chronicity, morbidity, and mortality. Recent advances in brain imaging research have led to an improved understanding of etiology and specific neurobiological mechanisms underlying symptoms. Despite this, there are no treatments focused on targeting symptoms using this empirically supported mechanistic understanding of the illness. Updated treatment approaches focused on targeting neurobiological mechanisms underlying core AN symptomatology are necessary to improve treatment out-comes for this population. Neurobiologically Enhanced With Family Eating Disorder Trait Response Treatment (NEW FED TR) is a neurobiologically informed treatment targeting key temperament constructs associated with the illness through the delivery of psychoeducation and skills training to patients and nominated carers.
神经性厌食症（AN）是一种严重且使人衰弱的疾病，会引发重大的医学和心理后遗症。迄今为止，针对成年人尚无有效的治疗方法，导致慢性化、发病率和死亡率居高不下。脑成像研究的最新进展使人们对该疾病的病因及症状背后的特定神经生物学机制有了更深入的了解。尽管如此，尚无基于对该疾病这种经验支持的机制性理解来针对症状的治疗方法。聚焦于针对神经性厌食症核心症状背后神经生物学机制的更新治疗方法对于改善这一人群的治疗效果是必要的。神经生物学强化家庭饮食失调特质反应治疗（NEW FED TR）是一种基于神经生物学的治疗方法，通过向患者及其指定照顾者提供心理教育和技能培训，针对与该疾病相关的关键气质结构。
