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[基于影像学的卒中介入治疗指征]

[Imaging-based indications for interventional treatment of stroke].

作者信息

Fiehler J, Thomalla G

机构信息

Klinik und Poliklinik für Neuroradiologische Diagnostik und Intervention, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.

Klinik und Poliklinik für Neurologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.

出版信息

Nervenarzt. 2015 Oct;86(10):1200-8. doi: 10.1007/s00115-015-4267-z.

DOI:10.1007/s00115-015-4267-z
PMID:26253441
Abstract

The indications for mechanical thrombectomy are based on a proximal vessel occlusion in the absence of extensive ischemic damage in the corresponding dependent vascular territory. The maximum extent of early ischemic edema for which endovascular treatment is still useful is not clear from the studies. A benefit of mechanical thrombectomy can be safely assumed with an ASPECT score of 6-10, possibly also with lower scores. A more complex imaging with assessment of the status of collateral vessels or perfusion abnormality is scientifically interesting but usually not necessary for clinical decision-making for endovascular stroke treatment within the first 6 h after symptom onset.

摘要

机械取栓的适应症基于近端血管闭塞且相应供血血管区域无广泛缺血损伤。目前的研究尚不清楚血管内治疗仍有效的早期缺血性水肿的最大范围。ASPECT评分为6 - 10分时,可以安全地认为机械取栓有益,评分更低时可能也有益。对侧支血管状态或灌注异常进行更复杂的成像在科学上很有意义,但对于症状发作后6小时内进行血管内卒中治疗的临床决策通常并非必要。

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2
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引用本文的文献

1
[Endovascular stroke treatment following recent positive clinical trials].[近期临床试验结果呈阳性后的血管内卒中治疗]
Nervenarzt. 2016 Apr;87(4):433-44; quiz 445-8. doi: 10.1007/s00115-015-0038-0.

本文引用的文献

1
Flat-Panel Computed Tomography (DYNA-CT) in Neuroradiology. From High-Resolution Imaging of Implants to One-Stop-Shopping for Acute Stroke.神经放射学中的平板计算机断层扫描(动态CT)。从植入物的高分辨率成像到急性中风的一站式服务。
Clin Neuroradiol. 2015 Oct;25 Suppl 2:291-7. doi: 10.1007/s00062-015-0423-x. Epub 2015 Jun 20.
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Endovascular therapy for ischemic stroke.缺血性卒中的血管内治疗
N Engl J Med. 2015 Jun 11;372(24):2366. doi: 10.1056/NEJMc1504715.
3
Thrombectomy in patients ineligible for iv tPA (THRILL).对不符合静脉注射组织型纤溶酶原激活剂(IV tPA)治疗条件的患者进行血栓切除术(THRILL)。
Int J Stroke. 2015 Aug;10(6):950-5. doi: 10.1111/ijs.12527. Epub 2015 Jun 4.
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Thrombectomy within 8 hours after symptom onset in ischemic stroke.发病 8 小时内进行缺血性脑卒中取栓治疗。
N Engl J Med. 2015 Jun 11;372(24):2296-306. doi: 10.1056/NEJMoa1503780. Epub 2015 Apr 17.
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Differential Effect of Baseline Computed Tomographic Angiography Collaterals on Clinical Outcome in Patients Enrolled in the Interventional Management of Stroke III Trial.基线计算机断层血管造影侧支循环对参与卒中干预管理III期试验患者临床结局的差异影响。
Stroke. 2015 May;46(5):1239-44. doi: 10.1161/STROKEAHA.115.009009. Epub 2015 Mar 19.
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Solitaire™ with the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME) trial: protocol for a randomized, controlled, multicenter study comparing the Solitaire revascularization device with IV tPA with IV tPA alone in acute ischemic stroke.以血栓切除术为主要血管内治疗手段治疗急性缺血性卒中的Solitaire™(SWIFT PRIME)试验:一项随机对照多中心研究方案,比较Solitaire血管再通装置联合静脉注射组织型纤溶酶原激活剂(IV tPA)与单纯静脉注射IV tPA治疗急性缺血性卒中的疗效。
Int J Stroke. 2015 Apr;10(3):439-48. doi: 10.1111/ijs.12459.
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Interventional stroke treatment: challenges after MR CLEAN.
Clin Neuroradiol. 2015 Mar;25(1):1. doi: 10.1007/s00062-015-0378-y.
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Endovascular therapy for ischemic stroke with perfusion-imaging selection.血管内治疗缺血性卒中的灌注成像选择。
N Engl J Med. 2015 Mar 12;372(11):1009-18. doi: 10.1056/NEJMoa1414792. Epub 2015 Feb 11.
9
A randomized trial of intraarterial treatment for acute ischemic stroke.急性缺血性脑卒中的动脉内治疗随机试验。
N Engl J Med. 2015 Jan 1;372(1):11-20. doi: 10.1056/NEJMoa1411587. Epub 2014 Dec 17.
10
Validity of acute stroke lesion volume estimation by diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomographic Score depends on lesion location in 496 patients with middle cerebral artery stroke.通过扩散加权成像-阿尔伯塔卒中项目早期计算机断层扫描评分对急性卒中病变体积进行估计的有效性取决于496例大脑中动脉卒中患者的病变位置。
Stroke. 2014 Dec;45(12):3583-8. doi: 10.1161/STROKEAHA.114.006694. Epub 2014 Oct 14.