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[血清CA-19-9放射免疫分析在胰腺癌诊断中的价值]

[Diagnostic value of radioimmunological analysis of CA-19-9 in the blood serum in cancer of the pancreas].

作者信息

Putseva N M, Chebotareva E D, Chernyĭ V A, Tashchiev R K

出版信息

Klin Khir (1962). 1989(11):15-7.

PMID:2625847
Abstract

The CA 19-9 antigen content was studied in 163 patients with pancreatic diseases by radioimmunologic method with the use of commercial test-kits ("Sorin", France). Pancreatitis was diagnosed in 67 patients, pancreatic cancer--in 23, cancer of the major duodenal papilla (MDP)--in 14, malignant neoplasms of the stomach, colon and rectum, liver--in 58. All the results were verified by morphologic studies. The control group included 22 donors. In patients with pancreatic cancer, the considerable increase in the CA 19-9 level was noted when compared with antigen content in the norm and in the other patients examined. The indices of CA 19-9 in pancreatitis don't differ from the normal ones. In MDP cancer and malignant tumours of other location with tumour invasion into the pancreas, the serum CA 19-9 level was increased.

摘要

采用法国“Sorin”商用检测试剂盒,通过放射免疫法对163例胰腺疾病患者的CA 19-9抗原含量进行了研究。67例患者被诊断为胰腺炎,23例为胰腺癌,14例为十二指肠乳头癌(MDP),58例为胃、结肠、直肠、肝癌。所有结果均经形态学研究验证。对照组包括22名献血者。与正常及其他受检患者的抗原含量相比,胰腺癌患者的CA 19-9水平显著升高。胰腺炎患者的CA 19-9指标与正常指标无差异。在MDP癌及肿瘤侵犯胰腺的其他部位恶性肿瘤中,血清CA 19-9水平升高。

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