Medvedenko A F, Shlopov V G, Shevchenko T I, Shevchenko N I, Adanian A A, Ostretsova N I
Klin Khir (1962). 1989(11):22-4.
All the 6 animals with the model of acute destructive pancreatitis died at day 2-3 from progressive pancreonecrosis, endogenous intoxication and dystrophic changes in the parenchymatous organs. After occlusion of the pancreatic ducts, acinous tissue atrophy began from the end of the second week, total atrophy occurred after 3 mos. Diabetes mellitus didn't develop for 2 years. Treatment of acute destructive pancreatitis by means of a full-value occlusion of the pancreatic ducts lead to recovery of the animals, and is perspective for the use in clinics.
所有6只患有急性坏死性胰腺炎模型的动物在第2 - 3天死于进行性胰腺坏死、内源性中毒和实质器官的营养不良性改变。胰腺导管闭塞后,腺泡组织萎缩从第二周结束时开始,3个月后出现完全萎缩。2年内未发生糖尿病。通过完全闭塞胰腺导管治疗急性坏死性胰腺炎可使动物康复,且在临床上有应用前景。