Alexiou D, Kauffmann J P, Arzoglou P L, Warter A, Ferard G, Karayannacos P, Skalkeas G R, Hollender L F
J Chir (Paris). 1982 Oct;119(10):597-602.
"Ethibloc" is a zeine-alcohol suspension which polymerizes in an aqueous medium after approximately 15 minutes. The product was injected in the pancreatic duct of 20 dogs. The procedure was free from complications, apart from the development of edematous pancreatitis without clinical manifestations. Healthy pancreases were transformed into fibrous organs within ten days or so, as is found in advanced stages of chronic pancreatitis. No effect occurred on the islets of Langerhans and a diabetes of the experimental type did'nt develop. "Ethibloc" would therefore appear to be of value in humans for the treatment of chronic pancreatitis, in order to reduce the period for transformation of the lesions without increasing the incidence of complications, and also for pancreatic fistulae of various origins, as a result of the rapid sclerosis of exocrine tissue that it provokes.
“Ethibloc”是一种玉米醇溶蛋白-酒精悬浮液，在大约15分钟后于水介质中聚合。该产品被注入20只狗的胰管。除了出现无临床表现的水肿性胰腺炎外，该操作无并发症发生。健康的胰腺在大约十天内就转变为纤维性器官，这与慢性胰腺炎晚期所见相同。对胰岛没有影响，也未发生实验性糖尿病。因此，“Ethibloc”在治疗人类慢性胰腺炎方面似乎具有价值，可减少病变转变的时间而不增加并发症的发生率，并且由于它能促使外分泌组织快速硬化，对各种原因引起的胰瘘也有治疗作用。
