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多发性阿米巴肝脓肿作为HIV血清阳性男性的初始表现

Multiple Amoebic Liver Abscess As Initial Manifestation in Hiv Sero-Positive Male.

作者信息

Chakrabarti Subrata

机构信息

Post Graduate Trainee, Department of General Medicine, Ipgmer , Kolkata, India .

出版信息

J Clin Diagn Res. 2015 Jun;9(6):OD04-5. doi: 10.7860/JCDR/2015/12043.6005. Epub 2015 Jun 1.

DOI:10.7860/JCDR/2015/12043.6005
PMID:26266151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4525540/
Abstract

Amoebic liver abscess is the most frequent extra-intestinal manifestation of Entamoeba histolytica infection. Immunosuppression is known to predispose to amoebic liver abscess. Although amoebic liver abscess is seen more commonly in patients of Human-Immunodeficiency virus (HIV), first presentation of HIV sero-positive patient as multiple liver abscess is quite uncommon.The author reports an unusual case of multiple liver abscesses in an HIV seropositive patient. This middle aged male with history of multiple unprotected sexual encounters presented with spasmodic abdominal pain, fever, diarrhoea and weight loss along with generalised ill-health and painful liver enlargement. HIV-1 serology was found to be reactive. Imaging revealed an enlarged liver with multiple, irregular, hypoechoic foci characteristic of abscesses. Amoebic aetiology was later confirmed by percutaneous aspiration and microscopy. Administration of appropriate chemotherapeutics along with institution of antiretroviral therapy led to both clinical resolution as well as disappearance of lesions.

摘要

阿米巴肝脓肿是溶组织内阿米巴感染最常见的肠外表现。已知免疫抑制易引发阿米巴肝脓肿。虽然阿米巴肝脓肿在人类免疫缺陷病毒(HIV)患者中更为常见,但HIV血清阳性患者首次表现为多发性肝脓肿相当罕见。作者报告了一例HIV血清阳性患者出现多发性肝脓肿的罕见病例。这名中年男性有多次无保护性行为史,出现痉挛性腹痛、发热、腹泻、体重减轻,伴有全身健康状况不佳和肝脏肿大疼痛。发现HIV-1血清学呈阳性反应。影像学检查显示肝脏肿大,有多个不规则的低回声病灶,具有脓肿特征。后来经皮穿刺抽吸和显微镜检查证实为阿米巴病因。给予适当的化疗药物并开始抗逆转录病毒治疗后,临床症状得到缓解,病变也消失了。

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本文引用的文献

1
Single and multiple liver abscesses in adults in Delhi are amoebic in origin: a clinical and microbiological study.德里成人单发性和多发性肝脓肿源于阿米巴:一项临床和微生物学研究。
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Amebiasis in HIV-1-infected Japanese men: clinical features and response to therapy.HIV-1 感染日本男性中的阿米巴病:临床特征和治疗反应。
PLoS Negl Trop Dis. 2011 Sep;5(9):e1318. doi: 10.1371/journal.pntd.0001318. Epub 2011 Sep 13.
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Amebic liver abscess in HIV-infected patients, Republic of Korea.韩国HIV感染患者的阿米巴肝脓肿
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Amoebic hepatic abscesses in an HIV-positive patient.一名HIV阳性患者的阿米巴肝脓肿
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A case of multiple amoebic liver abscesses: clinical improvement after percutaneous aspiration.一例多发性阿米巴肝脓肿:经皮穿刺抽吸术后临床症状改善
Acta Clin Belg. 2005 Jan-Feb;60(1):28-32.
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Causative agents of liver abscess in HIV-seropositive patients: a 10-year case series in Thai hospitalized patients.HIV 血清阳性患者肝脓肿的病原体:泰国住院患者的 10 年病例系列研究
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Amebic liver abscess and human immunodeficiency virus infection: a report of three cases.阿米巴肝脓肿与人类免疫缺陷病毒感染:三例报告
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