Chakrabarti Subrata
Post Graduate Trainee, Department of General Medicine, Ipgmer , Kolkata, India .
J Clin Diagn Res. 2015 Jun;9(6):OD04-5. doi: 10.7860/JCDR/2015/12043.6005. Epub 2015 Jun 1.
Amoebic liver abscess is the most frequent extra-intestinal manifestation of Entamoeba histolytica infection. Immunosuppression is known to predispose to amoebic liver abscess. Although amoebic liver abscess is seen more commonly in patients of Human-Immunodeficiency virus (HIV), first presentation of HIV sero-positive patient as multiple liver abscess is quite uncommon.The author reports an unusual case of multiple liver abscesses in an HIV seropositive patient. This middle aged male with history of multiple unprotected sexual encounters presented with spasmodic abdominal pain, fever, diarrhoea and weight loss along with generalised ill-health and painful liver enlargement. HIV-1 serology was found to be reactive. Imaging revealed an enlarged liver with multiple, irregular, hypoechoic foci characteristic of abscesses. Amoebic aetiology was later confirmed by percutaneous aspiration and microscopy. Administration of appropriate chemotherapeutics along with institution of antiretroviral therapy led to both clinical resolution as well as disappearance of lesions.
阿米巴肝脓肿是溶组织内阿米巴感染最常见的肠外表现。已知免疫抑制易引发阿米巴肝脓肿。虽然阿米巴肝脓肿在人类免疫缺陷病毒(HIV)患者中更为常见,但HIV血清阳性患者首次表现为多发性肝脓肿相当罕见。作者报告了一例HIV血清阳性患者出现多发性肝脓肿的罕见病例。这名中年男性有多次无保护性行为史,出现痉挛性腹痛、发热、腹泻、体重减轻,伴有全身健康状况不佳和肝脏肿大疼痛。发现HIV-1血清学呈阳性反应。影像学检查显示肝脏肿大,有多个不规则的低回声病灶,具有脓肿特征。后来经皮穿刺抽吸和显微镜检查证实为阿米巴病因。给予适当的化疗药物并开始抗逆转录病毒治疗后,临床症状得到缓解,病变也消失了。