Soentjens P, Ostyn B, Clerinx J, Van Gompel A, Colebunders R
Departement Interne Geneeskunde, Universitair Ziekenhuis Gasthuisberg, Herestraat 49, B-3000 Leuven.
Acta Clin Belg. 2005 Jan-Feb;60(1):28-32.
Amoebic liver abscesses are by far the most common extra-intestinal manifestation of invasive amoebiasis. The classical clinical picture consists of fever, right upper quadrant pain and hepatomegaly. Ultrasound and serology make an early diagnosis possible. Amoebic liver abscesses usually appear singly and are normally situated in the right lobe of the liver. This case report refers to a white Belgian woman, living in an endemic area for amoebiasis, presenting with 25 amoebic liver abscesses, who did not improve clinically despite appropriate anti-amoebic therapy, is described. Only percutaneous drainage of the larger abscesses led to clinical recovery. Amoebic abscess aspiration and evacuation under ultrasonographic guidance is of limited risk, but in experienced hands may enhance clinical recovery, particularly in patients with large abscesses not responding to conservative medical treatment. Aspiration of large abscesses (> 5 cm) is rarely necessary but should be considered if there is no clinical improvement after 3 days of nitroimidazole treatment with amoebicides.
阿米巴肝脓肿是目前侵袭性阿米巴病最常见的肠外表现。典型的临床症状包括发热、右上腹疼痛和肝肿大。超声检查和血清学检查有助于早期诊断。阿米巴肝脓肿通常单个出现,且多位于肝右叶。本文报告了一名居住在阿米巴病流行地区的比利时白人女性,她患有25个阿米巴肝脓肿,尽管接受了适当的抗阿米巴治疗,但临床症状并未改善。只有对较大的脓肿进行经皮引流才使病情临床痊愈。在超声引导下进行阿米巴脓肿穿刺抽脓和排脓风险有限,但在经验丰富的医生操作下可能会促进临床康复,尤其是对于那些对保守药物治疗无反应的大脓肿患者。抽吸大脓肿(>5厘米)很少有必要,但如果在用硝基咪唑类杀阿米巴药治疗3天后仍无临床改善,则应考虑进行抽吸。