Cachera J P, Abbou C, Deleuze P, Hillion M L, Loisance D, Romano P, Laurent F, Touzani A, Tavolaro O, Hittenger L
Department of Thoracic and Cardiovascular Surger, Hospital Henry-Mondor, Creteil, France.
Eur J Cardiothorac Surg. 1989;3(2):169-73; discussion 173-4. doi: 10.1016/1010-7940(89)90097-3.
A 45-year-old man received a combined heart and kidney transplant provided by the same donor. The patient was in the terminal stage of renal failure and was submitted to 3 sessions of haemodialysis per week for 2 years before transplantation. A dilated cardiomyopathy with severe impairment of left ventricular (LV) function was discovered, precluding renal transplantation alone. In the postoperative course, a cardiac rejection episode was detected by echocardiography and documented by endomyocardial biopsy; no simultaneous rejection of the kidney could be detected. The patient was discharged after 2 months, and he resumed a normal and active life. The specific problems raised by the management of such multi-organ transplantation are briefly reviewed.
一名45岁男性接受了来自同一供体的心脏和肾脏联合移植。该患者处于肾衰竭终末期,在移植前两年每周接受3次血液透析。发现患有扩张型心肌病,左心室(LV)功能严重受损,无法单独进行肾移植。在术后过程中,通过超声心动图检测到心脏排斥反应,并经心内膜活检证实;未检测到同时发生的肾脏排斥反应。患者在两个月后出院,恢复了正常且积极的生活。本文简要回顾了此类多器官移植管理中出现的具体问题。