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CTCF-binding elements 1 and 2 in the Igh intergenic control region cooperatively regulate V(D)J recombination.
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Super-enhancer transcription converges on AID.
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Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.
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A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping.
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IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances.
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Deep sequencing of the murine IgH repertoire reveals complex regulation of nonrandom V gene rearrangement frequencies.
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AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells.
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Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation.
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