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复发性自主神经反射异常的预防:当前实践调查

Prevention of recurrent autonomic dysreflexia: a survey of current practice.

作者信息

Caruso Deborah, Gater David, Harnish Christopher

机构信息

Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, USA.

Department of Veterans Affairs, Hunter Holmes McGuire Medical Center, 1201 Broad Rock Boulevard, Richmond, VA, 23249, USA.

出版信息

Clin Auton Res. 2015 Oct;25(5):293-300. doi: 10.1007/s10286-015-0303-0. Epub 2015 Aug 18.

DOI:10.1007/s10286-015-0303-0
PMID:26280219
Abstract

OBJECTIVE

There is a dearth of literature on the treatment of chronic recurrent autonomic dysreflexia (AD), a well-known complication of spinal cord injury that can have life-threatening implications. This study sought to identify clinical practices regarding the treatment of AD, both acute and recurrent, in patients with spinal cord injury (SCI).

METHODS

Online survey regarding AD management in SCI composed of 11 questions designed to obtain information on respondent characteristics, AD treatment options, and causes of AD.

SETTING

Veterans Administration health care system.

PARTICIPANTS

Veterans Health Administration National SCI Staff Physicians were sent an electronic email to participate in the anonymous web-based survey.

INTERVENTION

None applicable.

RESULTS

The response rate was 52%. The most commonly prescribed medications for minor and severe acute manifestations of AD were nitrates. For recurrent AD, clonidine was the most commonly prescribed medication.

INTERPRETATION

Anti-hypertensive medications continue to be the mainstay in the management of both acute and chronic recurrent AD. Current literature is lacking in prospective randomized controlled trials investigating the relative efficacy of AD interventions. Evidence-based practice guidelines are necessary to improve clinical care.

摘要

目的

关于慢性复发性自主神经反射异常(AD)的治疗,相关文献匮乏,AD是脊髓损伤的一种众所周知的并发症,可产生危及生命的后果。本研究旨在确定脊髓损伤(SCI)患者急性和复发性AD治疗的临床实践。

方法

关于SCI中AD管理的在线调查,由11个问题组成,旨在获取有关受访者特征、AD治疗选择和AD病因的信息。

地点

退伍军人管理局医疗保健系统。

参与者

向退伍军人健康管理局国家SCI staff Physicians发送电子邮件,邀请他们参与匿名的基于网络的调查。

干预措施

无。

结果

回复率为52%。AD轻度和重度急性表现最常用的药物是硝酸盐。对于复发性AD,可乐定是最常用的药物。

解读

抗高血压药物仍然是急性和慢性复发性AD管理的主要手段。目前的文献缺乏调查AD干预相对疗效的前瞻性随机对照试验。需要基于证据的实践指南来改善临床护理。

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Latest approaches for the treatment of spasticity and autonomic dysreflexia in chronic spinal cord injury.慢性脊髓损伤中痉挛和自主反射障碍的最新治疗方法。
Neurotherapeutics. 2011 Apr;8(2):274-82. doi: 10.1007/s13311-011-0025-5.
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Sacral rhizotomy: a salvage procedure in a patient with autonomic dysreflexia.骶神经根切断术:治疗自主反射障碍患者的挽救性手术。
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Smoking cessation pharmacotherapy.戒烟药物治疗
使用多模态非侵入性传感和神经网络自动检测和表征自主神经反射异常
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Autonomic Dysreflexia following Spinal Cord Injury.脊髓损伤后的自主神经反射异常
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Autonomic Dysfunction and Management after Spinal Cord Injury: A Narrative Review.脊髓损伤后的自主神经功能障碍及其管理:一项叙述性综述
J Pers Med. 2022 Jul 7;12(7):1110. doi: 10.3390/jpm12071110.
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Critical Care Management of Acute Spinal Cord Injury-Part II: Intensive Care to Rehabilitation.急性脊髓损伤的重症监护管理 - 第二部分:重症监护至康复
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Autonomic dysreflexia after spinal cord injury: Systemic pathophysiology and methods of management.脊髓损伤后的自主神经反射异常:全身病理生理学及管理方法
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Auton Neurosci. 2009 Mar 12;146(1-2):106-10. doi: 10.1016/j.autneu.2008.12.003. Epub 2009 Jan 20.
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