Livzan M A, Lyalukova E A, Nechaeva G, Osipenko M F, Dolgih T I
Eksp Klin Gastroenterol. 2015(3):34-8.
A research objective was the assessment of informational content of fecal noninvasive tests (calprotectin, transferrin, hemoglobin) in complex diagnosis of diseases of intestines. Open kogortny research by method of a cross cut included 52 patients (middle age - 38,6 years) with IBS-like symptoms (abdominal pain or discomfort, change of frequency and/or character of a chair). Sensitivity of dough on calprotectin for diagnosis of organic pathology of intestines made (89%), for dough on calprotectin and hemoglobin - also 89%. At patients at incomplete compliance of clinical signs to diagnostic criteria of IBS and lack of endoscopic signs of damage of a large intestine research on fecal biomarkers allows to increase efficiency of diagnostics.
一项研究目标是评估粪便非侵入性检测（钙卫蛋白、转铁蛋白、血红蛋白）在肠道疾病综合诊断中的信息含量。采用横断面方法进行的开放性队列研究纳入了52例有肠易激综合征样症状（腹痛或不适、大便频率和/或性状改变）的患者（中年 - 38.6岁）。粪便钙卫蛋白检测对肠道器质性病变诊断的敏感度为89%，粪便钙卫蛋白和血红蛋白检测的敏感度也为89%。对于临床症状不完全符合肠易激综合征诊断标准且无大肠损伤内镜征象的患者，粪便生物标志物研究可提高诊断效率。
